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Updates on the global dissemination of colistin-resistant Escherichia coli: An emerging threat to public health
Colistin drug resistance is an emerging public health threat worldwide. The adaptability,
existence and spread of colistin drug resistance in multiple reservoirs and ecological …
existence and spread of colistin drug resistance in multiple reservoirs and ecological …
Neonatal Sepsis: The Impact of Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae
The convergence of a vulnerable population and a notorious pathogen is devastating, as
seen in the case of sepsis occurring during the first 28 days of life (neonatal period). Sepsis …
seen in the case of sepsis occurring during the first 28 days of life (neonatal period). Sepsis …
Colistin kills bacteria by targeting lipopolysaccharide in the cytoplasmic membrane
Colistin is an antibiotic of last resort, but has poor efficacy and resistance is a growing
problem. Whilst it is well established that colistin disrupts the bacterial outer membrane (OM) …
problem. Whilst it is well established that colistin disrupts the bacterial outer membrane (OM) …
Antibiotics needed to treat multidrug-resistant infections in neonates
Infections remain a leading cause of death in neonates. The sparse antibiotic development
pipeline and challenges in conducting neonatal research have resulted in few effective …
pipeline and challenges in conducting neonatal research have resulted in few effective …
Treatment of Carbapenem-Resistant Enterobacteriaceae Infections in Children
Infections due to carbapenem-resistant Enterobacteriaceae (CRE) are increasingly
prevalent in children and are associated with poor clinical outcomes. Optimal treatment …
prevalent in children and are associated with poor clinical outcomes. Optimal treatment …
[HTML][HTML] Antibiotic resistance in paediatric febrile urinary tract infections
S Esposito, G Biasucci, A Pasini, B Predieri… - Journal of global …, 2022 - Elsevier
Febrile urinary tract infection (UTI) is currently considered the most frequent cause of serious
bacterial illness in children in the first 2 years of life. UTI in paediatrics can irreversibly …
bacterial illness in children in the first 2 years of life. UTI in paediatrics can irreversibly …
Carbapenem-resistant gram-negative bacterial infections in children
Carbapenem-resistant organisms (CRO) are a major global public health threat.
Enterobacterales hydrolyze almost all β-lactams through carbapenemase production …
Enterobacterales hydrolyze almost all β-lactams through carbapenemase production …
[HTML][HTML] Clinical use of intravenous polymyxin B for the treatment of patients with multidrug-resistant Gram-negative bacterial infections: An evaluation of the current …
Introduction The epidemic dimensions of emergence of multi-drug resistant Gram-negative
bacterial infections have led to the revival of old antibiotics, including polymyxins. Methods …
bacterial infections have led to the revival of old antibiotics, including polymyxins. Methods …
New antimicrobials for the treatment of neonatal sepsis caused by multi-drug-resistant bacteria: a systematic review
C Poggi, C Dani - Antibiotics, 2023 - mdpi.com
Background: Infections by multi-drug-resistant (MDR) organisms are sharply increasing in
newborns worldwide. In low and middle-income countries, a disproportionate amount of …
newborns worldwide. In low and middle-income countries, a disproportionate amount of …
Assessment of mortality-related risk factors and effective antimicrobial regimens for treatment of bloodstream infections caused by carbapenem-resistant …
L Chen, X Han, YL Li, M Li - Antimicrobial agents and …, 2021 - journals.asm.org
Bloodstream infections (BSIs) attributable to carbapenem-resistant Enterobacterales (CRE-
BSIs) are dangerous and a major cause of mortality in clinical settings. This study was …
BSIs) are dangerous and a major cause of mortality in clinical settings. This study was …