Mathematical modelling approaches have become increasingly abundant in cancer
research. The complexity of cancer is well suited to quantitative approaches as it provides …

Whether the nom de guerre is Mathematical Oncology, Computational or Systems Biology,
Theoretical Biology, Evolutionary Oncology, Bioinformatics, or simply Basic Science, there is …

Sex differences in the incidence and outcome of human disease are broadly recognized but,
in most cases, not sufficiently understood to enable sex-specific approaches to treatment …

Despite internal complexity, tumor growth kinetics follow relatively simple laws that can be
expressed as mathematical models. To explore this further, quantitative analysis of the most …

Adult gliomas are aggressive brain tumours associated with low patient survival rates and
limited life expectancy. The most important hallmark of this type of tumour is its invasive …

The most lethal form of brain cancer, glioblastoma multiforme, is characterized by rapid
growth and invasion facilitated by cell migration and degradation of the extracellular matrix …

Background High-grade gliomas are the most common primary brain tumours.
Pseudoprogression describes the false appearance of radiation-induced progression on …

Glioblastoma is the most aggressive form of brain tumor, accounting for the highest mortality
and morbidity rates. Current treatment for patients with glioblastoma includes maximal safe …

Glioblastoma (GBM) is a heterogeneous and lethal brain cancer. These tumors are followed
using magnetic resonance imaging (MRI), which is unable to precisely identify tumor cell …

Abstract Purpose: Response Evaluation Criteria in Solid Tumors (RECIST) evaluation does
not take into account the pretreatment tumor kinetics and may provide incomplete …