To counteract oxidative stress and associated brain diseases, antioxidant systems rescue
neuronal cells from oxidative stress by neutralizing reactive oxygen species and preserving …

Epilepsy has remained a significant social concern and financial burden globally. Current
therapeutic strategies are based primarily on neurocentric mechanisms that have not proven …

Fundamental work on the mechanisms leading to focal epileptic discharges in mesial
temporal lobe epilepsy (MTLE) often rests on the use of rodent models in which an initial …

Microglia are the resident immune cells of the center nervous system and participate in
various neurological diseases. Here we determined the function of microglia in …

Microglia are the resident immune cells in the brain that constitute the brain's innate immune
system. Recent studies have revealed various functions of microglia in the development and …

Extensive microglia reactivity has been well described in human and experimental temporal
lobe epilepsy (TLE). To date, however, it is not clear whether and based on which molecular …

Structural and functional collapse of the balance between excitatory (E) and inhibitory (I)
synapses, ie, synaptic E/I balance, underlies the pathogeneses of various central nervous …

Summary The Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT
XIII) took place in Madrid, Spain, on June 26–29, 2016, and was attended by> 200 …

Microglia are key players in maintaining brain homeostasis and exhibit phenotypic
alterations in response to epileptic stimuli. However, it is still relatively unknown if these …

Epilepsy is a common chronic consequence of traumatic brain injury (TBI), contributing to
increased morbidity and mortality for survivors. As post-traumatic epilepsy (PTE) is drug …