Ultrasound and microbubble mediated therapeutic delivery: Underlying mechanisms and future outlook
Beyond the emerging field of oncological ultrasound molecular imaging, the recent
significant advancements in ultrasound and contrast agent technology have paved the way …
significant advancements in ultrasound and contrast agent technology have paved the way …
Current advances in ultrasound-combined nanobubbles for cancer-targeted therapy: a review of the current status and future perspectives
C Su, XJ Ren, F Nie, T Li, W Lv, H Li, Y Zhang - RSC advances, 2021 - pubs.rsc.org
The non-specific distribution, non-selectivity towards cancerous cells, and adverse off-target
side effects of anticancer drugs and other therapeutic molecules lead to their inferior clinical …
side effects of anticancer drugs and other therapeutic molecules lead to their inferior clinical …
Nested nanobubbles for ultrasound-triggered drug release
DVB Batchelor, RH Abou-Saleh… - … applied materials & …, 2020 - ACS Publications
Because of their size (1–10 μm), microbubble-based drug delivery agents suffer from
confinement to the vasculature, limiting tumor penetration and potentially reducing the drug …
confinement to the vasculature, limiting tumor penetration and potentially reducing the drug …
Ultrasound-responsive lipid microbubbles for drug delivery: A review of preparation techniques to optimise formulation size, stability and drug loading
S Al-Jawadi, SS Thakur - International journal of pharmaceutics, 2020 - Elsevier
Lipid-shelled microbubbles have received extensive interest to enhance ultrasound-
responsive drug delivery outcomes due to their high biocompatibility. While therapeutic …
responsive drug delivery outcomes due to their high biocompatibility. While therapeutic …
[HTML][HTML] Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumor drug accumulation and limiting …
Most cancer patients receive chemotherapy at some stage of their treatment which makes
improving the efficacy of cytotoxic drugs an ongoing and important goal. Despite large …
improving the efficacy of cytotoxic drugs an ongoing and important goal. Despite large …
Pentacyclic triterpenoid phytochemicals with anticancer activity: Updated studies on mechanisms and targeted delivery
Pentacyclic triterpenoids (TTs) represent a unique family of phytochemicals with interesting
properties and pharmacological effects, with some representatives, such as betulinic acid …
properties and pharmacological effects, with some representatives, such as betulinic acid …
[HTML][HTML] Development of exosome membrane materials-fused microbubbles for enhanced stability and efficient drug delivery of ultrasound contrast agent
Y Jang, J Park, P Kim, EJ Park, H Sun, Y Baek… - … Pharmaceutica Sinica B, 2023 - Elsevier
Lipid-coated microbubbles are widely used as an ultrasound contrast agent, as well as drug
delivery carriers. However, the two main limitations in ultrasound diagnosis and drug …
delivery carriers. However, the two main limitations in ultrasound diagnosis and drug …
Acoustically-activated liposomal nanocarriers to mitigate the side effects of conventional chemotherapy with a focus on emulsion-liposomes
MN Zafar, WH Abuwatfa, GA Husseini - Pharmaceutics, 2023 - mdpi.com
To improve currently available cancer treatments, nanomaterials are employed as smart
drug delivery vehicles that can be engineered to locally target cancer cells and respond to …
drug delivery vehicles that can be engineered to locally target cancer cells and respond to …
[HTML][HTML] Horizon: Microfluidic platform for the production of therapeutic microbubbles and nanobubbles
RH Abou-Saleh, FJ Armistead… - Review of Scientific …, 2021 - pubs.aip.org
Microbubbles (MBs) have a multitude of applications including as contrast agents in
ultrasound imaging and as therapeutic drug delivery vehicles, with further scope for …
ultrasound imaging and as therapeutic drug delivery vehicles, with further scope for …
Microbubble–nanoparticle complexes for ultrasound-enhanced cargo delivery
Targeted delivery of therapeutics to specific tissues is critically important for reducing
systemic toxicity and optimizing therapeutic efficacy, especially in the case of cytotoxic …
systemic toxicity and optimizing therapeutic efficacy, especially in the case of cytotoxic …