[HTML][HTML] Overcoming Cancer Multi-drug Resistance (MDR): Reasons, mechanisms, nanotherapeutic solutions, and challenges

C Duan, M Yu, J Xu, BY Li, Y Zhao… - Biomedicine & …, 2023 - Elsevier
Multi-drug resistance (MDR) in cancer cells, either intrinsic or acquired through various
mechanisms, significantly hinders the therapeutic efficacy of drugs. Typically, the reduced …

Recent progress in nanomedicine for enhanced cancer chemotherapy

G Wei, Y Wang, G Yang, Y Wang, R Ju - Theranostics, 2021 - pmc.ncbi.nlm.nih.gov
As one of the most important cancer treatment strategies, conventional chemotherapy has
substantial side effects and leads easily to cancer treatment failure. Therefore, exploring and …

Supramolecular chemotherapy based on host–guest molecular recognition: a novel strategy in the battle against cancer with a bright future

J Zhou, G Yu, F Huang - Chemical Society Reviews, 2017 - pubs.rsc.org
Chemotherapy is currently one of the most effective ways to treat cancer. However,
traditional chemotherapy faces several obstacles to clinical trials, such as poor …

Poly (amidoamine)(PAMAM) dendrimer mediated delivery of drug and pDNA/siRNA for cancer therapy

J Li, H Liang, J Liu, Z Wang - International journal of pharmaceutics, 2018 - Elsevier
Abstract Poly (amidoamine)(PAMAM) dendrimers are well-defined, highly branched
macromolecules with numerous active amine groups on the surface. Because of their …

Metal‐coordinated supramolecular self‐assemblies for cancer theranostics

J Xu, J Wang, J Ye, J Jiao, Z Liu, C Zhao… - Advanced …, 2021 - Wiley Online Library
Metal‐coordinated supramolecular nanoassemblies have recently attracted extensive
attention as materials for cancer theranostics. Owing to their unique physicochemical …

Near-infrared light-triggered nano-prodrug for cancer gas therapy

R Liu, Y Peng, L Lu, S Peng, T Chen… - Journal of …, 2021 - Springer
Gas therapy (GT) has attracted increasing attention in recent years as a new cancer
treatment method with favorable therapeutic efficacy and reduced side effects. Several gas …

Pillararene-based supramolecular polymers for cancer therapy

M Yan, J Zhou - Molecules, 2023 - mdpi.com
Supramolecular polymers have attracted considerable interest due to their intriguing
features and functions. The dynamic reversibility of noncovalent interactions endows …

Metal-coordinated nanodrugs based on natural products for cancer theranostics

S Liu, X Xu, J Ye, J Wang, Q Wang, Z Liu, J Xu… - Chemical Engineering …, 2023 - Elsevier
Metal-coordinated nanodrugs based on natural products have recently attracted widespread
interests in cancer theranostics. Natural products have unparalleled advantages due to …

Cyclodextrin-based polymer materials: From controlled synthesis to applications

X Yao, P Huang, Z Nie - Progress in Polymer Science, 2019 - Elsevier
The design and construction of polymers with diverse architectures play an important role in
the field of polymer science and offers new opportunities for the development of novel …

Near-infrared light switching nitric oxide nanoemitter for triple-combination therapy of multidrug resistant cancer

G Wei, G Yang, B Wei, Y Wang, S Zhou - Acta Biomaterialia, 2019 - Elsevier
The multidrug resistance (MDR) of tumor cells often leads to the failure of chemotherapy
against cancer. It is urgently needed to develop a safe and effective strategy of overcoming …