Understanding bacterial biofilms: From definition to treatment strategies

A Zhao, J Sun, Y Liu - Frontiers in cellular and infection microbiology, 2023 - frontiersin.org
Bacterial biofilms are complex microbial communities encased in extracellular polymeric
substances. Their formation is a multi-step process. Biofilms are a significant problem in …

Bacterial biofilm and its role in the pathogenesis of disease

LK Vestby, T Grønseth, R Simm, LL Nesse - Antibiotics, 2020 - mdpi.com
Recognition of the fact that bacterial biofilm may play a role in the pathogenesis of disease
has led to an increased focus on identifying diseases that may be biofilm-related. Biofilm …

An updated conceptual model on the pathogenesis of bacterial vaginosis

CA Muzny, CM Taylor, WE Swords… - The Journal of …, 2019 - academic.oup.com
Bacterial vaginosis (BV) is the most common cause of vaginal discharge. It is associated
with an increased risk of preterm delivery, pelvic inflammatory disease, and an increased …

Roles of the microbiota of the female reproductive tract in gynecological and reproductive health

B Zhu, Z Tao, L Edupuganti, MG Serrano… - … and Molecular Biology …, 2022 - journals.asm.org
The microbiome of the female reproductive tract defies the convention that high biodiversity
is a hallmark of an optimal ecosystem. Although not universally true, a homogeneous …

Replication and refinement of a vaginal microbial signature of preterm birth in two racially distinct cohorts of US women

BJ Callahan, DB DiGiulio, DSA Goltsman… - Proceedings of the …, 2017 - pnas.org
Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality. Previous
studies have suggested that the maternal vaginal microbiota contributes to the …

Characterization of cervico-vaginal microbiota in women develo** persistent high-risk Human Papillomavirus infection

M Di Paola, C Sani, AM Clemente, A Iossa, E Perissi… - Scientific reports, 2017 - nature.com
Abstract Changes in cervico-vaginal microbiota with Lactobacillus depletion and increased
microbial diversity facilitate human papillomavirus (HPV) infection and might be involved in …

Bacterial vaginosis: a review of approaches to treatment and prevention

C Abbe, CM Mitchell - Frontiers in reproductive health, 2023 - frontiersin.org
Bacterial vaginosis (BV) is a common cause of vaginitis worldwide and is associated with
serious reproductive health outcomes, including increased risk of preterm birth, sexually …

Host–vaginal microbiota interactions in the pathogenesis of bacterial vaginosis

CA Muzny, P Łaniewski, JR Schwebke… - Current opinion in …, 2020 - journals.lww.com
Elucidating the cause of bacterial vaginosis has important implications for diagnosis and
treatment. Our current bacterial vaginosis pathogenesis model provides a framework for key …

Current treatment of bacterial vaginosis—limitations and need for innovation

CS Bradshaw, JD Sobel - The Journal of infectious diseases, 2016 - academic.oup.com
Practitioners and patients alike widely recognize the limitations of current therapeutic
approaches to the treatment of bacterial vaginosis (BV). Options remain extremely limited …

The reproductive microbiome: an emerging driver of sexual selection, sexual conflict, mating systems, and reproductive isolation

M Rowe, L Veerus, P Trosvik, A Buckling… - Trends in ecology & …, 2020 - cell.com
All multicellular organisms host microbial communities in and on their bodies, and these
microbiomes can have major influences on host biology. Most research has focussed on the …