Innate immunity in the middle ear mucosa

HM Massa, KM Spann, AW Cripps - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
Otitis media (OM) encompasses a spectrum of clinical presentations ranging from the readily
identifiable Acute OM (AOM), which is characterised by otalgia and fever, to chronic otitis …

ISOM 2023 research Panel 4-Diagnostics and microbiology of otitis media

SO Tamir, S Bialasiewicz, CG Brennan-Jones… - International Journal of …, 2023 - Elsevier
Objectives To identify and review key research advances from the literature published
between 2019 and 2023 on the diagnosis and microbiology of otitis media (OM) including …

Case-control microbiome study of chronic otitis media with effusion in children points at streptococcus salivarius as a pathobiont-inhibiting species

J Jörissen, MFL van den Broek, I De Boeck… - …, 2021 - journals.asm.org
Chronic otitis media with effusion (OME) has been associated with a shift in microbiome
composition and microbial interaction in the upper respiratory tract (URT). While most …

Role of cytokines and Th17/Tregs imbalance in the pathogenesis of otitis media with effusion. Modulation of Notch1/Hes1/mTORC1/S6k1 signalling pathway underlies …

NM Mohamed, AM Abdelhamid, M Aref… - International …, 2024 - Elsevier
Otitis media with effusion (OME) is a recurrent middle ear inflammatory condition. It may be
complicated by acquired hearing loss and speech impairment especially in children …

Otitis media: Interactions between host and environment, immune and inflammatory responses

J Nokso-Koivisto, GD Ehrlich, F Enoksson… - International journal of …, 2024 - Elsevier
Objective To review and highlight progress in otitis media (OM) research in the areas of
immunology, inflammation, environmental influences and host-pathogen responses from …

Characterization of middle ear microbiome in otitis media with effusion in Hungarian children: Alloiococcus otitidis may potentially hamper the microbial diversity

S Fekete, J Juhász, N Makra, ZA Dunai, K Kristóf… - Heliyon, 2024 - cell.com
Introduction Although otitis media with effusion (OME) is a common cause of hearing
impairment in children, little is known about its microbiological background. We aimed to …

PANEL 3: otitis media animal models, cell culture, tissue regeneration & pathophysiology

A Kurabi, K Dewan, JE Kerschner, A Leichtle… - International Journal of …, 2024 - Elsevier
Objective To review and summarize recently published key articles on the topics of animal
models, cell culture studies, tissue biomedical engineering and regeneration, and new …

Corynebacteria from the respiratory microbiota modulate inflammatory responses and associate with a reduced pneumococcal burden in the lungs

C Bergenfelz, P Do, L Larsson, H Ivarsson… - Frontiers in Cellular …, 2025 - frontiersin.org
Background Certain species from the normal respiratory tract microbiota have recently been
proposed to positively influence human health. Corynebacterium propinquum and C …

Nasopharyngeal microbiome analyses in otitis-prone and otitis-free children

L Xu, J Earl, P Bajorski, E Gonzalez… - International Journal of …, 2021 - Elsevier
Abstract Objectives About 10–15% children develop frequent acute otitis media (AOM)
confirmed by tympanocentesis. These children are designated sOP (stringently defined otitis …