Clinical and biological insights from viral genome sequencing
Whole-genome sequencing (WGS) of pathogens is becoming increasingly important not
only for basic research but also for clinical science and practice. In virology, WGS is …
only for basic research but also for clinical science and practice. In virology, WGS is …
Detecting biothreat agents: From current diagnostics to develo** sensor technologies
Although a fundamental understanding of the pathogenicity of most biothreat agents has
been elucidated and available treatments have increased substantially over the past …
been elucidated and available treatments have increased substantially over the past …
NCBI viral genomes resource
JR Brister, D Ako-Adjei, Y Bao… - Nucleic acids …, 2015 - academic.oup.com
Recent technological innovations have ignited an explosion in virus genome sequencing
that promises to fundamentally alter our understanding of viral biology and profoundly …
that promises to fundamentally alter our understanding of viral biology and profoundly …
Noroviruses—the state of the art, nearly fifty years after their initial discovery
LF Ludwig-Begall, A Mauroy, E Thiry - Viruses, 2021 - mdpi.com
Human noroviruses are recognised as the major global cause of viral gastroenteritis. Here,
we provide an overview of notable advances in norovirus research and provide a short …
we provide an overview of notable advances in norovirus research and provide a short …
Emergence of norovirus strains: A tale of two genes
GI Parra - Virus Evolution, 2019 - academic.oup.com
Noroviruses are a very diverse group of viruses that infect different mammalian species. In
humans, norovirus is a major cause of acute gastroenteritis. Multiple norovirus infections can …
humans, norovirus is a major cause of acute gastroenteritis. Multiple norovirus infections can …
Rapid emergence and predominance of a broadly recognizing and fast-evolving norovirus GII. 17 variant in late 2014
Norovirus genogroup II genotype 4 (GII. 4) has been the predominant cause of viral
gastroenteritis since 1996. Here we show that during the winter of 2014–2015, an emergent …
gastroenteritis since 1996. Here we show that during the winter of 2014–2015, an emergent …
An atlas of continuous adaptive evolution in endemic human viruses
KE Kistler, T Bedford - Cell host & microbe, 2023 - cell.com
Through antigenic evolution, viruses such as seasonal influenza evade recognition by
neutralizing antibodies. This means that a person with antibodies well tuned to an initial …
neutralizing antibodies. This means that a person with antibodies well tuned to an initial …
Detection of respiratory viruses directly from clinical samples using next‐generation sequencing: A literature review of recent advances and potential for routine …
Acute respiratory infection is the third most frequent cause of mortality worldwide, causing
over 4.25 million deaths annually. Although most diagnosed acute respiratory infections are …
over 4.25 million deaths annually. Although most diagnosed acute respiratory infections are …
High throughput sequencing for the detection and characterization of RNA viruses
This review aims to assess and recommend approaches for targeted and agnostic High
Throughput Sequencing of RNA viruses in a variety of sample matrices. HTS also referred to …
Throughput Sequencing of RNA viruses in a variety of sample matrices. HTS also referred to …
Human norovirus proteins: implications in the replicative cycle, pathogenesis, and the host immune response
Human noroviruses (HuNoVs) are the cause of more than 95% of epidemic non-bacterial
gastroenteritis worldwide, with some lethal cases. These viral agents affect people of all …
gastroenteritis worldwide, with some lethal cases. These viral agents affect people of all …