The many faces of solitary fibrous tumor; diversity of histological features, differential diagnosis and role of molecular studies and surrogate markers in avoiding …

MU Tariq, NU Din, J Abdul-Ghafar, YK Park - Diagnostic Pathology, 2021‏ - Springer
Abstract Background Solitary Fibrous Tumor (SFT) is a distinct soft tissue neoplasm
associated with NAB2-STAT6 gene fusion. It can involve a number of anatomic sites and …

[HTML][HTML] A comprehensive review on solitary fibrous tumor: new insights for new horizons

J Martin-Broto, JL Mondaza-Hernandez, DS Moura… - Cancers, 2021‏ - mdpi.com
Simple Summary Solitary fibrous tumor (SFT) is a malignant condition that exhibits different
clinical behaviors ranging from low to high aggressive SFT, with dedifferentiated SFT (DD …

[HTML][HTML] Risk assessment in solitary fibrous tumors: validation and refinement of a risk stratification model

EG Demicco, MJ Wagner, RG Maki, V Gupta, I Iofin… - Modern Pathology, 2017‏ - Elsevier
Solitary fibrous tumors are an uncommon sarcoma type characterized by NAB2–STAT6
gene fusion. While solitary fibrous tumors metastasize in 5–25% of cases, it has historically …

Extrapleural solitary fibrous tumor: a distinct entity from pleural solitary fibrous tumor. An update on clinical, molecular and diagnostic features

A Ronchi, I Cozzolino, FZ Marino, M Accardo… - Annals of Diagnostic …, 2018‏ - Elsevier
Solitary fibrous tumor (SFT) is a mesenchymal neoplasm that was originally described to be
localized in the pleura, but thereafter, this has been reported in several anatomic sites …

Extensive survey of STAT6 expression in a large series of mesenchymal tumors

EG Demicco, PW Harms, RM Patel… - American journal of …, 2015‏ - academic.oup.com
Objectives: Expression of strong nuclear STAT6 is thought to be a specific marker for solitary
fibrous tumors (SFTs). Little is known about subtle expression patterns in other …

[HTML][HTML] Novel therapeutic options for solitary fibrous tumor: antiangiogenic therapy and beyond

A de Bernardi, A Dufresne, F Mishellany, JY Blay… - Cancers, 2022‏ - mdpi.com
Simple Summary In the latest WHO classification, solitary fibrous tumors (SFTs) are now
subdivided into benign SFT (intermediate category (locally aggressive)), SFT NOS …

[HTML][HTML] Prediction of local and metastatic recurrence in solitary fibrous tumor: construction of a risk calculator in a multicenter cohort from the French Sarcoma Group …

S Salas, N Resseguier, JY Blay, A Le Cesne… - Annals of oncology, 2017‏ - Elsevier
Background Solitary fibrous tumors (SFT) are rare unusual ubiquitous soft tissue tumors that
are presumed to be of fibroblastic differentiation. At present, the challenge is to establish …

[HTML][HTML] NAB2–STAT6 fusion types account for clinicopathological variations in solitary fibrous tumors

HC Tai, IC Chuang, TC Chen, CF Li, SC Huang… - Modern Pathology, 2015‏ - Elsevier
Solitary fibrous tumor (SFT) is characterized by the inv12 (q13q13)-derived NAB2–STAT6
fusion, which exhibits variable breakpoints and drives STAT6 nuclear expression. The …

The current status of solitary fibrous tumor: diagnostic features, variants, and genetics

K Thway, W Ng, J Noujaim… - … Journal of Surgical …, 2016‏ - journals.sagepub.com
Solitary fibrous tumor (SFT) is a fibroblastic mesenchymal tumor originally described in the
pleura but now shown at almost every anatomic site. Histopathologically, SFT is …

Distinct clinicopathological features of NAB2-STAT6 fusion gene variants in solitary fibrous tumor with emphasis on the acquisition of highly malignant potential

K Akaike, A Kurisaki-Arakawa, K Hara, Y Suehara… - Human pathology, 2015‏ - Elsevier
The impact of NGFI-A binding protein 2 (NAB2)-signal transducer and activator of
transcription 6 (STAT6) fusion on the biological behavior and the mechanism of acquisition …