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Therapeutic opportunities and challenges in targeting the orphan G protein-coupled receptor GPR35
GPR35 is a class A, rhodopsin-like G protein-coupled receptor (GPCR) first identified more
than 20 years ago. In the intervening period, identification of strong expression in the lower …
than 20 years ago. In the intervening period, identification of strong expression in the lower …
[HTML][HTML] Chemogenetic Tools and their Use in Studies of Neuropsychiatric Disorders
M Neřoldová, A Stuchlík - Physiological Research, 2024 - pmc.ncbi.nlm.nih.gov
Chemogenetics is a newly developed set of tools that allow for selective manipulation of cell
activity. They consist of a receptor mutated irresponsive to endogenous ligands and a …
activity. They consist of a receptor mutated irresponsive to endogenous ligands and a …