Beyond Mortality: Exploring the Influence of Plant Phenolics on Modulating Ferroptosis—A Systematic Review

N Živanović, M Lesjak, N Simin, SKS Srai - Antioxidants, 2024 - mdpi.com
Ferroptosis is a recently discovered type of programmed cell death that is mechanistically
different from other types of programmed cell death such as apoptosis, necroptosis, and …

[HTML][HTML] Nuclear factor erythroid 2-related factor-mediated signaling alleviates ferroptosis during cerebral ischemia-reperfusion injury

Z Li, J **ng - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Cardiac arrest (CA) is a significant challenge for emergency physicians worldwide and leads
to increased morbidity and mortality rates. The poor prognosis of CA primarily stems from the …

Sea buckthorn extract mitigates chronic obstructive pulmonary disease by suppression of ferroptosis via scavenging ROS and blocking p53/MAPK pathways

L Liu, T Wen, Y **ao, H Chen, S Yang… - Journal of …, 2025 - Elsevier
Abstract Ethnopharmacological relevance Sea buckthorn (Hippophae rhamnoides), a
traditional Tibetan medicinal herb, exhibits protective effects against cardiovascular and …

A comprehensive review of ferroptosis in environmental pollutants-induced chronic obstructive pulmonary disease

X Jiang, Z Peng, B He, S Li, Q Huang - Science of The Total Environment, 2024 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a common chronic lung disease that
impacts hundreds of millions of individuals worldwide. It is principally characterized by …

In vitro and in vivo activities of scutellarein, a novel polyphosphate kinase 1 inhibitor against Acinetobacter baumannii infection

Y Song, H Lv, L Xu, Z Liu, J Wang, T Fang, X Deng… - Microbial Cell …, 2024 - Springer
Background Inorganic polyphosphate (polyP)-targeted polyphosphate kinase 1 (PPK1) has
attracted much attention by virtue of its importance in bacterial pathogenicity and …

[HTML][HTML] DsbA-L deficiency promotes cigarette smoke-induced bronchial epithelial cells ferroptosis by inhibiting catalase in COPD

S Li, Z Peng, Q Huang, Q Chen, B He - Environmental Technology & …, 2025 - Elsevier
Background Ferroptosis, characterized by iron-dependent programmed cell death, has been
implicated in chronic obstructive pulmonary disease (COPD). Recent studies have shown …

[HTML][HTML] Natural flavonoids act as potent ferroptosis inhibitors and their potentials in the treatment of ferroptosis-associated diseases

L Liu, L Wang, Y **ao, Y Liu, X Meng, X Shen - … Research-Modern Chinese …, 2024 - Elsevier
Backgrounds Ferroptosis, an iron-dependent cell death characterized by lethal lipid
peroxidation, has been involved in the pathogenesis of various diseases, such as …

Scutellarein ameliorates dextran sulfate sodium-induced ulcerative colitis by inhibiting colonic epithelial cell proinflammation and barrier disruption

Q Tang, H Jia, X Qin, Z Lu, W Huang… - Frontiers in …, 2024 - frontiersin.org
Introduction Scutellarein (Scu) is a natural occurring flavonoid found in multiple traditional
Chinese medicines such as Oroxylum indicum (L.) Kurz and Scutellaria baicalensis, with …

[HTML][HTML] The molecular and metabolic landscape of ferroptosis in respiratory diseases: Pharmacological aspects

T Wu, M Ji, T Li, L Luo - Journal of Pharmaceutical Analysis, 2024 - Elsevier
Ferroptosis is a form of cell death that occurs when there is an excess of reactive oxygen
species (ROS), lipid peroxidation, and iron accumulation. The precise regulation of …

Scutellarein alleviates osteoarthritis progression through the PI3K/Akt/NF‐kappaB signaling pathway: In vitro and in vivo studies

Z Ye, Z Ge, S Yang, T Hu, Q Ye… - Phytotherapy …, 2024 - Wiley Online Library
Osteoarthritis (OA), a joint disease that is associated with inflammatory processes is involved
in joint destruction. Scutellarein (Scu), a component of the medicinal herbs Scutellaria …