The first paper on “inflammaging” published in 2001 paved the way for a unifying theory on
how and why aging turns out to be the main risk factor for the development of the most …

Inflammation is a complicated biological and pathophysiological cascade of responses to
infections and injuries, and inflammatory mechanisms are closely related to many diseases …

Abstract Angiopoietin-like 4 (ANGPTL4) is known to regulate various cellular and systemic
functions. However, its cell-specific role in endothelial cells (ECs) function and metabolic …

Objective To investigate the lung cancer-promoting mechanism of mesenchymal stem cell-
secreted extracellular vesicles (MSC-EV). Methods EV were isolated from culture media of …

Arterial stiffness predicts an increased risk of cardiovascular events. Inflammation plays a
major role in large arteries stiffening, related to atherosclerosis, arteriosclerosis, endothelial …

Efficient clearance of apoptotic cells, termed efferocytosis, critically regulates normal
homeostasis whereas defective uptake of apoptotic cells results in chronic and non …

Background Hypoxia is a major cause of beta cell death and dysfunction after
transplantation. The aim of this study was to investigate the effect of exosomes derived from …

Atherosclerosis is a chronic inflammatory disorder characterized by the gradual build-up of
plaques within the vessel wall of middle-sized and large arteries. Over the past decades …

Ambient air pollution, and especially particulate matter (PM) air pollution< 2.5 μm in
diameter (PM 2.5), has clearly emerged as an important yet often overlooked risk factor for …

Atherosclerosis underlies the predominant number of cardiovascular diseases and remains
a leading cause of morbidity and mortality worldwide. The development, progression and …