A significant decrease in estrogen levels puts menopausal women at high risk for major
depression, which remains difficult to cure despite its relatively clear etiology. With the …

Clinical studies have shown that women are more susceptible to depression than men. Sex
differences in depression have been associated with social, cultural, as well as biological …

Alzheimer's disease (AD) is characterized by an active inflammatory response induced by
the brain's deposition and accumulation of amyloid-beta (Aβ). Cannabinoid receptor type 2 …

Neuroinflammation mediated by microglia activation is a critical contributor to Alzheimer's
disease (AD) pathogenesis. Dysregulated microglia polarization in terms of M1 …

Depression is an overwhelming health concern, and many patients fail to optimally respond
to available standard therapies. Neuroplasticity and blood–brain barrier (BBB) integrity are …

Erigeron bonariensis is widely distributed throughout the world's tropics and subtropics. In
folk medicine, E. bonariensis has historically been used to treat head and brain diseases …

The peri-and post-menopausal periods have been described as the “window of
vulnerability” for the development of depressive symptoms that impair women activities and …

Aims Roflumilast, a well-known phosphodiesterase-4 (PDE-4) inhibitor, possess an anti-
inflammatory activity with approved indications in chronic obstructive pulmonary disease …

Maternal deprivation for 24 h produces an immediate increase in basal and stress-induced
corticosterone (CORT) secretion. Given the impact of elevated CORT levels on brain …

The present study was performed to evaluate the efficacy of nanonutraceuticals (NN) for
attenuation of neurobehavioral and neurochemical abnormalities in Alzheimer's disease …