Innovations in biomaterials and stem cell technology have allowed for the emergence of
novel three-dimensional (3D) tissue-like structures known as organoids and spheroids. As a …

Metastasis is a complex, multistep process responsible for> 90% of cancer-related deaths. In
addition to genetic and external environmental factors, the physical interactions of cancer …

Focal adhesions (FAs) connect inner workings of cell to the extracellular matrix to control cell
adhesion, migration and mechanosensing. Previous studies demonstrated that FAs contain …

Red blood cells, or erythrocytes, are seen to flicker under optical microscopy, a
phenomenon initially described as thermal fluctuations of the cell membrane. But recent …

In situ, cells are highly sensitive to geometrical and mechanical constraints from their
microenvironment. These parameters are, however, uncontrolled under classic culture …

The functions of caveolae, the characteristic plasma membrane invaginations, remain
debated. Their abundance in cells experiencing mechanical stress led us to investigate their …

Here we present an active patterning technique named “acoustic tweezers” that utilizes
standing surface acoustic wave (SSAW) to manipulate and pattern cells and microparticles …

Integrin-containing focal adhesions transmit extracellular signals across the plasma
membrane to modulate cell adhesion, signalling and survival. Although integrins are known …

The response of cells to forces is essential for tissue morphogenesis and homeostasis. This
response has been extensively investigated in interphase cells, but it remains unclear how …

Recent achievements and future opportunities for the design of 2D, 3D, and 4D materials
using photochemical reactions are summarized. Light is an attractive stimulus for material …