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Increased risk for the development of preeclampsia in obese pregnancies: weighing in on the mechanisms
Preeclampsia (PE) is a pregnancy-specific disorder typically presenting as new-onset
hypertension and proteinuria. While numerous epidemiological studies have demonstrated …
hypertension and proteinuria. While numerous epidemiological studies have demonstrated …
Pyoderma gangrenosum and pregnancy: an example of abnormal inflammation and challenging treatment
RB Steele, WH Nugent, SF Braswell… - British Journal of …, 2016 - academic.oup.com
Pyoderma gangrenosum (PG) is a neutrophil‐predominant inflammatory disease that
initially presents as a sterile pustule and may progress to ulcerations. Its root cause is …
initially presents as a sterile pustule and may progress to ulcerations. Its root cause is …
Methods for the use of progestogen as a glucocorticoid sensitizer
TT Du - US Patent 10,231,976, 2019 - Google Patents
Provided are methods and kits for administering progesto gen as a glucocorticoid sensitizer
to restore corticosteroid sensitivity or reverse the glucocorticoid insensitivity or enhance …
to restore corticosteroid sensitivity or reverse the glucocorticoid insensitivity or enhance …
RUPP Th17s cause hypertension and mitochondrial dysfunction in the kidney and placenta during pregnancy
Abstract Background Preeclampsia (PE), new-onset hypertension (HTN), and organ
dysfunction during the second half of pregnancy, is associated with an increase in …
dysfunction during the second half of pregnancy, is associated with an increase in …
Evaluation of IL-17 and IL-35 serum levels in patients with preeclampsia
Background: Pre-eclampsia (PE) is the most common pregnancy complication affecting 2–
8% of all pregnancies. PE could lead to maternal and prenatal morbidity. Imbalanced …
8% of all pregnancies. PE could lead to maternal and prenatal morbidity. Imbalanced …
Treating auto-immune and auto-inflammatory diseases
TT Du, C Lee - US Patent 10,987,361, 2021 - Google Patents
The present invention relates to the formulations, methods and kits for reducing cytokine
interleukin-17 (IL-17 or IL-17A) levels in both broncheoalveolar lavage fluid (BALF) and …
interleukin-17 (IL-17 or IL-17A) levels in both broncheoalveolar lavage fluid (BALF) and …
Pulmonary delivery of progestogen
C Lee, TT Du - US Patent 10,993,879, 2021 - Google Patents
The present invention relates to a pharmaceutical formula tion powder that contains 17c-
hydroxyprogesterone caproate (17-OHPC) powder and the method of producing the …
hydroxyprogesterone caproate (17-OHPC) powder and the method of producing the …