[HTML][HTML] TGF-β and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and disease

M Wu, G Chen, YP Li - Bone research, 2016 - nature.com
Transforming growth factor-beta (TGF-β) and bone morphogenic protein (BMP) signaling
has fundamental roles in both embryonic skeletal development and postnatal bone …

Cell signaling and transcriptional regulation of osteoblast lineage commitment, differentiation, bone formation, and homeostasis

S Zhu, W Chen, A Masson, YP Li - Cell Discovery, 2024 - nature.com
The initiation of osteogenesis primarily occurs as mesenchymal stem cells undergo
differentiation into osteoblasts. This differentiation process plays a crucial role in bone …

Defective S‐TiO2−x/CeO2 Heterojunction for Mutual Reinforcing Chemodynamic/Sonocatalytic Antibacterial Therapy and Sonoelectric/Ion‐Activated Bone …

C Wang, J Lei, C Mao, S Wu, Y Zheng… - Advanced Functional …, 2023 - Wiley Online Library
Sonocatalysis and chemodynamics have attracted widespread attention in antibacterial
therapy. The transfer efficiency of electrons plays an important role in sonocatalysis and …

Progress of Wnt signaling pathway in osteoporosis

Y Gao, N Chen, Z Fu, Q Zhang - Biomolecules, 2023 - mdpi.com
Osteoporosis, one of the serious health diseases, involves bone mass loss, bone density
diminishing, and degeneration of bone microstructure, which is accompanied by a tendency …

Wnt pathway in bone repair and regeneration–what do we know so far

KS Houschyar, C Tapking, MR Borrelli… - Frontiers in cell and …, 2019 - frontiersin.org
Wnt signaling plays a central regulatory role across a remarkably diverse range of functions
during embryonic development, including those involved in the formation of bone and …

The role of the wnt/β-catenin signaling pathway in formation and maintenance of bone and teeth

P Duan, LF Bonewald - The international journal of biochemistry & cell …, 2016 - Elsevier
The Wnt signaling pathway is known as one of the important molecular cascades that
regulate cell fate throughout lifespan. The Wnt signaling pathway is further separated into …

Understanding of dopant-induced osteogenesis and angiogenesis in calcium phosphate ceramics

S Bose, G Fielding, S Tarafder… - Trends in …, 2013 - cell.com
General trends in synthetic bone grafting materials are shifting towards approaches that can
illicit osteoinductive properties. Pharmacologics and biologics have been used in …

Role of Wnt signaling and sclerostin in bone and as therapeutic targets in skeletal disorders

F Marini, F Giusti, G Palmini, ML Brandi - Osteoporosis International, 2023 - Springer
Wnt signaling and its bone tissue–specific inhibitor sclerostin are key regulators of bone
homeostasis. The therapeutic potential of anti-sclerostin antibodies (Scl-Abs), for bone mass …

BMP signalling: agony and antagony in the family

DP Brazil, RH Church, S Surae, C Godson, F Martin - Trends in cell biology, 2015 - cell.com
Bone morphogenetic proteins (BMPs) are secreted extracellular matrix (ECM)-associated
proteins that regulate a wide range of developmental processes, including limb and kidney …

Multifunctional magnesium incorporated scaffolds by 3D-Printing for comprehensive postsurgical management of osteosarcoma

J Long, W Zhang, Y Chen, B Teng, B Liu, H Li, Z Yao… - Biomaterials, 2021 - Elsevier
Clinical treatment of Osteosarcoma (OS) encounters great challenges of postsurgical tumor
recurrence and extensive bone defect. To address these issues, innovative multifunctional …