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Structural and functional diversity of type IV secretion systems
Considerable progress has been made in recent years in the structural and molecular
biology of type IV secretion systems in Gram-negative bacteria. The latest advances have …
biology of type IV secretion systems in Gram-negative bacteria. The latest advances have …
[HTML][HTML] Legionella pneumophila: The Journey from the Environment to the Blood
V Iliadi, J Staykova, S Iliadis, I Konstantinidou… - Journal of Clinical …, 2022 - mdpi.com
An outbreak of a potentially fatal form of pneumonia in 1976 and in the annual convention of
the American Legion was the first time that Legionella spp. was identified. Thereafter, the …
the American Legion was the first time that Legionella spp. was identified. Thereafter, the …
Nitric oxide signaling through three receptors regulates virulence, biofilm formation, and phenotypic heterogeneity of Legionella pneumophila
S Michaelis, T Chen, C Schmid, H Hilbi - MBio, 2024 - journals.asm.org
The causative agent of Legionnaires' disease, Legionella pneumophila, is an environmental
bacterium, that replicates in macrophages, parasitizes amoeba, and forms biofilms. L …
bacterium, that replicates in macrophages, parasitizes amoeba, and forms biofilms. L …
Small molecule communication of Legionella: the ins and outs of autoinducer and nitric oxide signaling
S Michaelis, L Gomez-Valero, T Chen… - Microbiology and …, 2024 - journals.asm.org
Legionella pneumophila is a Gram-negative environmental bacterium, which survives in
planktonic form, colonizes biofilms, and infects protozoa. Upon inhalation of Legionella …
planktonic form, colonizes biofilms, and infects protozoa. Upon inhalation of Legionella …
Protein sociology of ProA, Mip and other secreted virulence factors at the Legionella pneumophila surface
The pathogenicity of L. pneumophila, the causative agent of Legionnaires' disease, depends
on an arsenal of interacting proteins. Here we describe how surface-associated and …
on an arsenal of interacting proteins. Here we describe how surface-associated and …
Bactericidal effectors of the Stenotrophomonas maltophilia type IV secretion system: functional definition of the nuclease TfdA and structural determination of TfcB
Stenotrophomonas maltophilia expresses a type IV protein secretion system (T4SS) that
promotes contact-dependent killing of other bacteria and does so partly by secreting the …
promotes contact-dependent killing of other bacteria and does so partly by secreting the …
The large GTPase Sey1/atlastin mediates lipid droplet-and FadL-dependent intracellular fatty acid metabolism of Legionella pneumophila
D Hüsler, P Stauffer, B Keller, D Böck, T Steiner… - Elife, 2023 - elifesciences.org
The amoeba-resistant bacterium Legionella pneumophila causes Legionnaires' disease
and employs a type IV secretion system (T4SS) to replicate in the unique, ER-associated …
and employs a type IV secretion system (T4SS) to replicate in the unique, ER-associated …
Global atlas of predicted functional domains in Legionella pneumophila Dot/Icm translocated effectors
Legionella pneumophila utilizes the Dot/Icm type IVB secretion system to deliver hundreds
of effector proteins inside eukaryotic cells to ensure intracellular replication. Our …
of effector proteins inside eukaryotic cells to ensure intracellular replication. Our …
Tap** lipid droplets: A rich fat diet of intracellular bacterial pathogens
D Hüsler, P Stauffer, H Hilbi - Molecular microbiology, 2023 - Wiley Online Library
Lipid droplets (LDs) are dynamic and versatile organelles present in most eukaryotic cells.
LDs consist of a hydrophobic core of neutral lipids, a phospholipid monolayer coat, and a …
LDs consist of a hydrophobic core of neutral lipids, a phospholipid monolayer coat, and a …
The Legionella autoinducer LAI-1 is delivered by outer membrane vesicles to promote interbacterial and interkingdom signaling
Legionella pneumophila is an environmental bacterium, which replicates in amoeba but
also in macrophages, and causes a life-threatening pneumonia called Legionnaires' …
also in macrophages, and causes a life-threatening pneumonia called Legionnaires' …