Sebaceous immunobiology-skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations

CC Zouboulis, T Coenye, L He, K Kabashima… - Frontiers in …, 2022 - frontiersin.org
This review presents several aspects of the innovative concept of sebaceous
immunobiology, which summarizes the numerous activities of the sebaceous gland …

Homeostasis of the sebaceous gland and mechanisms of acne pathogenesis

RW Clayton, K Göbel, CM Niessen… - British Journal of …, 2019 - academic.oup.com
Summary Background Sebaceous glands (SGs) are appendages of mammalian skin that
produce a mixture of lipids known as sebum. Acne vulgaris is an exceptionally common skin …

[HTML][HTML] Single-cell transcriptomics reveals that differentiation and spatial signatures shape epidermal and hair follicle heterogeneity

S Joost, A Zeisel, T Jacob, X Sun, G La Manno… - Cell systems, 2016 - cell.com
The murine epidermis with its hair follicles represents an invaluable model system for tissue
regeneration and stem cell research. Here we used single-cell RNA-sequencing to reveal …

Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments

MA Goodell, H Nguyen, N Shroyer - Nature reviews Molecular cell …, 2015 - nature.com
Somatic stem cells replenish many tissues throughout life to repair damage and to maintain
tissue homeostasis. Stem cell function is frequently described as following a hierarchical …

Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury

NA Veniaminova, YY Jia, AM Hartigan, TJ Huyge… - Cell reports, 2023 - cell.com
Sebaceous glands (SGs) release oils that protect our skin, but how these glands respond to
injury has not been previously examined. Here, we report that SGs are largely self-renewed …

Sex bias in autoimmunity

AC Billi, JM Kahlenberg… - Current opinion in …, 2019 - journals.lww.com
Sex bias in autoimmunity : Current Opinion in Rheumatology Sex bias in autoimmunity :
Current Opinion in Rheumatology Log in or Register Subscribe to journalSubscribe Get …

Meibomian gland stem/progenitor cells: the hunt for gland renewal

X Yang, LW Reneker, X Zhong, AJW Huang… - The Ocular Surface, 2023 - Elsevier
Meibomian glands (MGs) secrete lipid (meibum) onto the ocular surface to form the
outermost layer of the tear film. Proper meibum secretion is essential for stabilizing the tear …

Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties

G Donati, E Rognoni, T Hiratsuka, K Liakath-Ali… - Nature cell …, 2017 - nature.com
The epidermis is maintained by multiple stem cell populations whose progeny differentiate
along diverse, and spatially distinct, lineages. Here we show that the transcription factor …

Neuroendocrinology and neurobiology of sebaceous glands

RW Clayton, EA Langan, DM Ansell… - Biological …, 2020 - Wiley Online Library
The nervous system communicates with peripheral tissues through nerve fibres and the
systemic release of hypothalamic and pituitary neurohormones. Communication between …

Pathogenesis of wound healing disorders in the elderly

E Makrantonaki, M Wlaschek… - JDDG: Journal der …, 2017 - Wiley Online Library
The elderly constitute the age group most susceptible to wound healing disorders and
chronic wounds, the most prevalent being venous leg ulcers, pressure ulcers, and diabetic …