Sebaceous immunobiology-skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations
This review presents several aspects of the innovative concept of sebaceous
immunobiology, which summarizes the numerous activities of the sebaceous gland …
immunobiology, which summarizes the numerous activities of the sebaceous gland …
Homeostasis of the sebaceous gland and mechanisms of acne pathogenesis
RW Clayton, K Göbel, CM Niessen… - British Journal of …, 2019 - academic.oup.com
Summary Background Sebaceous glands (SGs) are appendages of mammalian skin that
produce a mixture of lipids known as sebum. Acne vulgaris is an exceptionally common skin …
produce a mixture of lipids known as sebum. Acne vulgaris is an exceptionally common skin …
[HTML][HTML] Single-cell transcriptomics reveals that differentiation and spatial signatures shape epidermal and hair follicle heterogeneity
The murine epidermis with its hair follicles represents an invaluable model system for tissue
regeneration and stem cell research. Here we used single-cell RNA-sequencing to reveal …
regeneration and stem cell research. Here we used single-cell RNA-sequencing to reveal …
Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments
Somatic stem cells replenish many tissues throughout life to repair damage and to maintain
tissue homeostasis. Stem cell function is frequently described as following a hierarchical …
tissue homeostasis. Stem cell function is frequently described as following a hierarchical …
Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury
NA Veniaminova, YY Jia, AM Hartigan, TJ Huyge… - Cell reports, 2023 - cell.com
Sebaceous glands (SGs) release oils that protect our skin, but how these glands respond to
injury has not been previously examined. Here, we report that SGs are largely self-renewed …
injury has not been previously examined. Here, we report that SGs are largely self-renewed …
Sex bias in autoimmunity
Sex bias in autoimmunity : Current Opinion in Rheumatology Sex bias in autoimmunity :
Current Opinion in Rheumatology Log in or Register Subscribe to journalSubscribe Get …
Current Opinion in Rheumatology Log in or Register Subscribe to journalSubscribe Get …
Meibomian gland stem/progenitor cells: the hunt for gland renewal
X Yang, LW Reneker, X Zhong, AJW Huang… - The Ocular Surface, 2023 - Elsevier
Meibomian glands (MGs) secrete lipid (meibum) onto the ocular surface to form the
outermost layer of the tear film. Proper meibum secretion is essential for stabilizing the tear …
outermost layer of the tear film. Proper meibum secretion is essential for stabilizing the tear …
Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties
The epidermis is maintained by multiple stem cell populations whose progeny differentiate
along diverse, and spatially distinct, lineages. Here we show that the transcription factor …
along diverse, and spatially distinct, lineages. Here we show that the transcription factor …
Neuroendocrinology and neurobiology of sebaceous glands
RW Clayton, EA Langan, DM Ansell… - Biological …, 2020 - Wiley Online Library
The nervous system communicates with peripheral tissues through nerve fibres and the
systemic release of hypothalamic and pituitary neurohormones. Communication between …
systemic release of hypothalamic and pituitary neurohormones. Communication between …
Pathogenesis of wound healing disorders in the elderly
E Makrantonaki, M Wlaschek… - JDDG: Journal der …, 2017 - Wiley Online Library
The elderly constitute the age group most susceptible to wound healing disorders and
chronic wounds, the most prevalent being venous leg ulcers, pressure ulcers, and diabetic …
chronic wounds, the most prevalent being venous leg ulcers, pressure ulcers, and diabetic …