Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection. Over decades, advanced …

The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

Inflammation is a complex set of interactions among soluble factors and cells that can arise
in any tissue in response to traumatic, infectious, post-ischaemic, toxic or autoimmune injury …

Sepsis is a condition that results from a harmful or damaging host response to infection.
Many of the components of the innate immune response that are normally concerned with …

Hemostasis encompasses the tightly regulated processes of blood clotting, platelet
activation, and vascular repair. After wounding, the hemostatic system engages a plethora of …

Endothelial cells, which form the inner cellular lining of blood vessels and lymphatics,
display remarkable heterogeneity in structure and function. This is the first of a 2-part review …

A quick literature search in the MEDLINE databases from 1966 to 1998 using the search
term disseminated intravascular coagulation (DIC) and related key words yields an …

Sepsis is a life-threatening clinical syndrome characterized by multiorgan dysfunction
caused by a dysregulated or over-reactive host response to infection. During sepsis, the …

Severe sepsis, defined as sepsis with acute organ dysfunction, is associated with high
morbidity and mortality rates. The development of novel therapies for sepsis is critically …

The diagnosis of disseminated intravascular coagulation (DIC) should encompass both
clinical and laboratory information. The International Society for Thrombosis and …