Reinforcement learning in healthcare: A survey

C Yu, J Liu, S Nemati, G Yin - ACM Computing Surveys (CSUR), 2021 - dl.acm.org
As a subfield of machine learning, reinforcement learning (RL) aims at optimizing decision
making by using interaction samples of an agent with its environment and the potentially …

Nonequilibrium physics in biology

X Fang, K Kruse, T Lu, J Wang - Reviews of Modern Physics, 2019 - APS
Life is characterized by a myriad of complex dynamic processes allowing organisms to grow,
reproduce, and evolve. Physical approaches for describing systems out of thermodynamic …

A chaos study of tumor and effector cells in fractional tumor-immune model for cancer treatment

S Kumar, A Kumar, B Samet, JF Gómez-Aguilar… - Chaos, Solitons & …, 2020 - Elsevier
A tumor is most dangerous disease of medical science which is a mass or lumps of tissue
that's formed by an accumulation of abnormal cells. A famous fractional tumor-immune …

Assessing the interactions between radiotherapy and antitumour immunity

C Grassberger, SG Ellsworth, MQ Wilks… - Nature reviews Clinical …, 2019 - nature.com
Immunotherapy, specifically the introduction of immune checkpoint inhibitors, has
transformed the treatment of cancer, enabling long-term tumour control even in individuals …

Tumour immunotherapy: lessons from predator–prey theory

PT Hamilton, BR Anholt, BH Nelson - Nature Reviews Immunology, 2022 - nature.com
With the burgeoning use of immune-based treatments for cancer, never has there been a
greater need to understand the tumour microenvironment within which immune cells …

Revolutionizing cancer treatment: Comprehensive insights into immunotherapeutic strategies

NR Raghani, MR Chorawala, M Mahadik, RB Patel… - Medical Oncology, 2024 - Springer
Cancer, characterized by the uncontrolled proliferation of aberrant cells, underscores the
imperative for innovative therapeutic approaches. Immunotherapy has emerged as a pivotal …

Mathematical modeling of tumor-immune cell interactions

GE Mahlbacher, KC Reihmer, HB Frieboes - Journal of Theoretical Biology, 2019 - Elsevier
The anti-tumor activity of the immune system is increasingly recognized as critical for the
mounting of a prolonged and effective response to cancer growth and invasion, and for …

Multiscale agent-based and hybrid modeling of the tumor immune microenvironment

KA Norton, C Gong, S Jamalian, AS Popel - Processes, 2019 - mdpi.com
Multiscale systems biology and systems pharmacology are powerful methodologies that are
playing increasingly important roles in understanding the fundamental mechanisms of …

Mathematical models for immunology: current state of the art and future research directions

R Eftimie, JJ Gillard, DA Cantrell - Bulletin of mathematical biology, 2016 - Springer
The advances in genetics and biochemistry that have taken place over the last 10 years led
to significant advances in experimental and clinical immunology. In turn, this has led to the …

Mathematical models of tumor cell proliferation: A review of the literature

AM Jarrett, EABF Lima, DA Hormuth… - Expert review of …, 2018 - Taylor & Francis
Introduction: A defining hallmark of cancer is aberrant cell proliferation. Efforts to understand
the generative properties of cancer cells span all biological scales: from genetic deviations …