Preeclampsia: Recent advances in predicting, preventing, and managing the maternal and fetal life-threatening condition

KJ Chang, KM Seow, KH Chen - International journal of environmental …, 2023 - mdpi.com
Preeclampsia accounts for one of the most common documented gestational complications,
with a prevalence of approximately 2 to 15% of all pregnancies. Defined as gestational …

Vascular dysfunction in preeclampsia

MA Opichka, MW Rappelt, DD Gutterman, JL Grobe… - Cells, 2021 - mdpi.com
Preeclampsia is a life-threatening pregnancy-associated cardiovascular disorder
characterized by hypertension and proteinuria at 20 weeks of gestation. Though its exact …

Early prediction of preeclampsia in pregnancy with cell-free RNA

MN Moufarrej, SK Vorperian, RJ Wong, AA Campos… - Nature, 2022 - nature.com
Liquid biopsies that measure circulating cell-free RNA (cfRNA) offer an opportunity to study
the development of pregnancy-related complications in a non-invasive manner and to …

The International Federation of Gynecology and Obstetrics (FIGO) initiative on preeclampsia (PE): a pragmatic guide for first trimester screening and prevention

LC Poon, A Shennan, JA Hyett, A Kapur… - … of gynaecology and …, 2019 - pmc.ncbi.nlm.nih.gov
Preeclampsia (PE) is a multisystem disorder that typically affects 2%− 5% of pregnant
women and is one of the leading causes of maternal and perinatal morbidity and mortality …

Aspirin use to prevent preeclampsia and related morbidity and mortality: updated evidence report and systematic review for the US Preventive Services Task Force

JT Henderson, KK Vesco, CA Senger, RG Thomas… - Jama, 2021 - jamanetwork.com
Importance Preeclampsia is a hypertensive disorder of pregnancy that poses serious
maternal and infant health risks. Previous systematic reviews have established benefits of …

Prevention of preeclampsia with aspirin

DL Rolnik, KH Nicolaides, LC Poon - American journal of obstetrics and …, 2022 - Elsevier
Preeclampsia is defined as hypertension arising after 20 weeks of gestational age with
proteinuria or other signs of end-organ damage and is an important cause of maternal and …

First trimester preeclampsia screening and prediction

P Chaemsaithong, DS Sahota, LC Poon - American journal of obstetrics …, 2022 - Elsevier
Preeclampsia is a major cause of maternal and perinatal morbidity and mortality. Early-onset
disease requiring preterm delivery is associated with a higher risk of complications in both …

[HTML][HTML] Imbalances in circulating angiogenic factors in the pathophysiology of preeclampsia and related disorders

S Rana, SD Burke, SA Karumanchi - American journal of obstetrics and …, 2022 - Elsevier
Preeclampsia is a devastating medical complication of pregnancy that can lead to significant
maternal and fetal morbidity and mortality. It is currently believed that there is abnormal …

Regulatory T cells in embryo implantation and the immune response to pregnancy

SA Robertson, AS Care, LM Moldenhauer - The Journal of clinical …, 2018 - jci.org
At implantation, the embryo expresses paternally derived alloantigens and evokes
inflammation that can threaten reproductive success. To ensure a robust placenta and …

Financial toll of untreated perinatal mood and anxiety disorders among 2017 births in the United States

DL Luca, C Margiotta, C Staatz… - … journal of public …, 2020 - ajph.aphapublications.org
Objectives. To estimate the economic burden of untreated perinatal mood and anxiety
disorders (PMADs) among 2017 births in the United States. Methods. We developed a …