Microbes are typically surrounded by different strains and species with whom they compete
for scarce nutrients and limited space. Given such challenging living conditions, microbes …

Most microbial communities consist of a genetically diverse assembly of different organisms,
and the level of genetic diversity plays an important part in community properties and …

INTRODUCTION Microbial populations display heterogeneous gene expression profiles that
result in phenotypic differences between individual bacteria. This diversity can allow …

Pseudomonas aeruginosa, a leading cause of severe hospital-acquired pneumonia, causes
infections with up to 50% mortality rates in mechanically ventilated patients. Despite some …

Serovars of Salmonella enterica cause both gastrointestinal and systemic diseases in a
broad range of mammalian hosts, including humans. Salmonella virulence depends in part …

Antibiotic treatment failure is of growing concern. Genetically encoded resistance is key in
driving this process. However, there is increasing evidence that bacterial antibiotic …

Persisters are transiently tolerant variants that allow populations to avoid eradication by
antibiotic treatment. Their antibiotic tolerance is non-genetic, not inheritable and results from …

Multicellularity is characterized by cooperation among cells for the development,
maintenance and reproduction of the multicellular organism. Cancer can be viewed as …

For decades, mankind has dominated the battle against bacteria, yet the tide is slowly
turning. Our antibacterial strategies are becoming less effective, allowing bacteria to get the …

Bacterial infection leads to consumption of short-lived innate immune effector cells, which
then need to be replenished from hematopoietic stem and progenitor cells (HSPCs). HSPCs …