Strong evidence suggests that early-life exposures to suboptimal environmental factors,
including those in utero, influence our long-term metabolic health. This has been termed …

Mitochondria are of great relevance to health, and their dysregulation is associated with
major chronic diseases. Research on mitochondria—156 brand new publications from 2019 …

Mitochondrial DNA (mtDNA) harbors essential genes in most metazoans, yet the regulatory
impact of the multiple evolutionary mtDNA rearrangements has been overlooked. Here, by …

Mitochondria are multifaceted organelles which are important for bioenergetics,
biosynthesis, and signaling in metazoans. Mitochondrial functions are frequently altered in …

Introduction: Obtaining triphenylphosphonium salts derived from anticancer compounds to
inhibit mitochondrial metabolism is of major interest due to their pivotal role in reactive …

Mitochondrial dysfunction has been reported in monogenic phenotypes, but also as part of
common complex disorders. Explanations for the underlying mechanism of both disease …

Mitochondria are essential in eukaryotes. Besides producing 80% of total cellular ATP,
mitochondria are involved in various cellular functions such as apoptosis, inflammation …

Deoxygenation, the reduction of oxygen level in the oceans induced by global warming and
anthropogenic disturbances, is a major threat to marine life. This change in oxygen level …

The infectious agent for African trypanosomiasis, Trypanosoma brucei, possesses a unique
and essential translocase of the mitochondrial inner membrane, known as the TbTIM17 …

This article provides an updated review on the evolution of mitochondria from bacteria,
which were likely related to extant alphaproteobacteria. Particular attention is given to the …