Background Various bioactive aromatic compounds containing the indole nucleus showed
clinical and biological applications. Indole scaffold has been found in many of the important …

Cancer chemotherapy is frequently hampered by drug resistance, so the resistance to
anticancer agents represents one of the major obstacles for the effective cancer treatment …

Tetrahydro‐β‐carbolines (THβCs) also known as tryptolines serve as important structural
elements in natural products and pharmaceutical compounds, and they are also utilized in …

Malaria has been a major parasitic disease in tropical and subtropical regions and is
estimated to kill between one and two million people (mainly children) every year. Novel anti …

Melatonin is a natural hormone primarily released by the pineal gland that regulates the
sleep-wake cycles. The diverse biological applications of melatonin, together with the need …

Sulfonamides constitute an important class of drugs, with many types of pharmacological
agents possessing antibacterial, anti-carbonic anhydrase, anti-obesity, diuretic …

Malaria is a tropical disease, leading to around half a million deaths annually. Antimalarials
such as quinolines are crucial to fight against malaria, but malaria control is extremely …

The emergence and worldwide spread of drug‐resistant bacteria have already posed a
serious threat to human life, creating the urgent need to develop potent and novel …

An important bioactive heterocycle having several uses in medicinal chemistry, synthetic
organic chemistry, material chemistry, and natural product is indole along with its analogues …

Malaria is a major parasitic disease in tropical and sub-tropical regions. Pertaining to the
sustaining resistance in malarial parasite against the available drugs, novel treatment …