[HTML][HTML] The translational genetics of ADHD and related phenotypes in model organisms
J Cabana-Domínguez, E Antón-Galindo… - … & biobehavioral reviews, 2023 - Elsevier
Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent neurodevelopmental
disorder resulting from the interaction between genetic and environmental risk factors. It is …
disorder resulting from the interaction between genetic and environmental risk factors. It is …
[HTML][HTML] Alternative models for transgenerational epigenetic inheritance: Molecular psychiatry beyond mice and man
Mental illness remains the greatest chronic health burden globally with few in-roads having
been made despite significant advances in genomic knowledge in recent decades. The field …
been made despite significant advances in genomic knowledge in recent decades. The field …
The Use of Drosophila to Understand Psychostimulant Responses
TJ Philyaw, A Rothenfluh, I Titos - Biomedicines, 2022 - mdpi.com
The addictive properties of psychostimulants such as cocaine, amphetamine,
methamphetamine, and methylphenidate are based on their ability to increase …
methamphetamine, and methylphenidate are based on their ability to increase …
Genotype and Trait Specific Responses to Rapamycin Intake in Drosophila melanogaster
PD Rohde, A Bøcker, CAB Jensen, AL Bergstrøm… - Insects, 2021 - mdpi.com
Simple Summary Rapamycin is commonly used as an immunosuppressant, but also as an
anti-aging medicine. Despite its widespread use, results suggest that there is large …
anti-aging medicine. Despite its widespread use, results suggest that there is large …
EasyFlyTracker: A Simple Video Tracking Python Package for Analyzing Adult Drosophila Locomotor and Sleep Activity to Facilitate Revealing the Effect of …
S Qu, Q Zhu, H Zhou, Y Gao, Y Wei, Y Ma… - Frontiers in Behavioral …, 2022 - frontiersin.org
The mechanism of psychiatric drugs (stimulant and non-stimulant) is still unclear. Precision
medication of psychiatric disorders faces challenges in pharmacogenetics and …
medication of psychiatric disorders faces challenges in pharmacogenetics and …
The effects of methylphenidate and atomoxetine on Drosophila brain at single-cell resolution and potential drug repurposing for ADHD treatment
S Qu, X Zhou, Z Wang, Y Wei, H Zhou, X Zhang… - Molecular …, 2024 - nature.com
The stimulant methylphenidate (MPH) and the non-stimulant atomoxetine (ATX) are
frequently used for the treatment of attention-deficit/hyperactivity disorder (ADHD); however …
frequently used for the treatment of attention-deficit/hyperactivity disorder (ADHD); however …
Prediction of complex phenotypes using the Drosophila melanogaster metabolome
Understanding the genotype–phenotype map and how variation at different levels of
biological organization is associated are central topics in modern biology. Fast …
biological organization is associated are central topics in modern biology. Fast …
[HTML][HTML] Bugs on Drugs: Paracetamol Exposure Reveals Genotype-Specific Generational Effects on Life History Traits in Drosophila melanogaster
Simple Summary In this study, we used the vinegar fly, Drosophila melanogaster, as a
genetic model to investigate the potential long-lasting consequences of exposure to …
genetic model to investigate the potential long-lasting consequences of exposure to …
Untangling the genetic basis of drug response
We are all unique! This is evident in the immediate differences in our appearances, from
variability in individual disease predisposition and disease trajectories, to molecular defined …
variability in individual disease predisposition and disease trajectories, to molecular defined …
Susu Qu1, 2*†, Qingjie Zhu2†, Han Zhou2, Yuan Gao2, Yi Wei2, Yuan Ma2, Zhicheng Wang1, 2, Xueting Sun2, Lei Zhang2, 3, Quanjun Yang4, Lei Kong5 and Li …
BRH Geurten, BH Paffhausen… - Modern Methods in …, 2022 - books.google.com
Drosophila is a powerful genetic animal model for studies of complex phenotypes such as
circadian rhythms, sleep, movement, and diseases (Sokolowski, 2001; Bier, 2005; Bellen et …
circadian rhythms, sleep, movement, and diseases (Sokolowski, 2001; Bier, 2005; Bellen et …