Uterine fibroids are benign monoclonal neoplasms of the myometrium, representing the
most common tumors in women worldwide. To date, no long-term or noninvasive treatment …

The extracellular matrix (ECM) is a highly dynamic system that constantly offers physical,
biological, and chemical signals to embraced cells. Increasing evidence suggests that …

Cells in the body reside within the extracellular matrix (ECM), a three-dimensional
environment that not only provides structural support for the cells, but also influences cellular …

Actin plays roles in many important cellular processes, including cell motility, organelle
movement, and cell signaling. The discovery of transmembrane actin-binding proteins at the …

Ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) DNA
damage response (DDR) kinases contain elastic domains. ATM also responds to reactive …

Proteins are molecular machines that provide structure and perform vital transport, signalling
and enzymatic roles. Proteins expressed by cells require tight regulation of their …

Intrinsic and innate immune responses are essential lines of defense in the body's constant
surveillance of pathogens. The discovery of liquid–liquid phase separation (LLPS) as a key …

In addition to biochemical signals and genetic considerations, mechanical forces are rapidly
emerging as a master regulator of human physiology. However, the molecular mechanisms …

Active biomaterials offer novel approaches to study mechanotransduction in mammalian
cells. These material systems probe cellular responses by dynamically modulating their …

Nuclear lamins are type‐V intermediate filaments that are involved in many nuclear
processes. In mammals, A‐and B‐type lamins assemble into separate physical meshwork …