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A spotlight on the interplay of signaling pathways and the role of miRNAs in osteosarcoma pathogenesis and therapeutic resistance
Osteosarcoma (OS) is one of the most common bone cancers that constantly affects
children, teenagers, and young adults. Numerous epigenetic elements, such as miRNAs …
children, teenagers, and young adults. Numerous epigenetic elements, such as miRNAs …
Current status and prospects of clinical treatment of osteosarcoma
ZY Jiang, JB Liu, XF Wang, YS Ma… - Technology in cancer …, 2022 - journals.sagepub.com
Osteosarcoma, one of the common malignant tumors in the skeletal system, originates in
mesenchymal tissue, and the most susceptible area of occurrence is the metaphysis with its …
mesenchymal tissue, and the most susceptible area of occurrence is the metaphysis with its …
MicroRNAs; their therapeutic and biomarker properties
MicroRNAs (miRNAs) are, small (roughly 19–25 nucleotides in length), conserved, non-
coding, single-stranded, and functional RNA molecules with the properties of gene …
coding, single-stranded, and functional RNA molecules with the properties of gene …
Targeting signaling pathways in osteosarcoma: Mechanisms and clinical studies
Z Ji, J Shen, Y Lan, Q Yi, H Liu - MedComm, 2023 - Wiley Online Library
Osteosarcoma (OS) is a highly prevalent bone malignancy among adolescents, accounting
for 40% of all primary malignant bone tumors. Neoadjuvant chemotherapy combined with …
for 40% of all primary malignant bone tumors. Neoadjuvant chemotherapy combined with …
Anti-invasive and anti-migratory effects of ononin on human osteosarcoma cells by limiting the MMP2/9 and EGFR-Erk1/2 pathway
G Gong, K Ganesan, Q **ong, Y Zheng - Cancers, 2023 - mdpi.com
Simple Summary Osteosarcoma is the most prevalent orthotopic bone tumor. Due to its high
metastatic properties, it has become the leading cause of cancer death worldwide. At this …
metastatic properties, it has become the leading cause of cancer death worldwide. At this …
Zinc oxide nanoparticles and cancer chemotherapy: Helpful tools for enhancing chemo-sensitivity and reducing side effects?
Cancer chemotherapy is still a serious challenge. Chemo-resistance and destructive side
effects of chemotherapy drugs are the most critical limitations of chemotherapy. Chemo …
effects of chemotherapy drugs are the most critical limitations of chemotherapy. Chemo …
Nanostructured system based on hydroxyapatite and curcumin: A promising candidate for osteosarcoma therapy
Osteosarcoma is the most common type of bone cancer. Despite therapeutic progress,
survival rates for metastatic cases or that do not respond well to chemotherapy remain in the …
survival rates for metastatic cases or that do not respond well to chemotherapy remain in the …
[HTML][HTML] Research progress on the role of lncRNA, circular RNA, and microRNA networks in regulating ferroptosis in osteosarcoma
C Yan, Y Dou, R **a, S Liu, J Fu, D Li, R Wang… - Biomedicine & …, 2024 - Elsevier
Noncoding RNAs (ncRNAs) do not participate in protein-coding. Ferroptosis is a newly
discovered form of cell death mediated by reactive oxygen species and lipid peroxidation …
discovered form of cell death mediated by reactive oxygen species and lipid peroxidation …
[HTML][HTML] MAT2A inhibits the ferroptosis in osteosarcoma progression regulated by miR-26b-5p
S **a, Y Liang, Y Shen, W Zhong, Y Ma - Journal of Bone Oncology, 2023 - Elsevier
Osteosarcoma (OS) is the most frequent primary malignant bone tumor. Ferroptosis, a form
of regulated cell death, is a key tumor suppression mechanism. Although methionine …
of regulated cell death, is a key tumor suppression mechanism. Although methionine …
Target recycle initiated entropy driven assembly strategy for sensitive, enzyme-free, and portable miRNA detection
Z Jiang, Z Liu - Analytical Biochemistry, 2024 - Elsevier
MicroRNA (miRNA) is a pivotal biomarker in the diagnosis of various cancers, including
bladder cancer (BCa). Despite their significance, the low abundance of miRNA presents a …
bladder cancer (BCa). Despite their significance, the low abundance of miRNA presents a …