Allergen immunotherapy is a cornerstone in the treatment of allergic children. The clinical
efficiency relies on a well‐defined immunologic mechanism promoting regulatory T cells and …

House dust mites are an unsurpassed cause of atopic sensitization and allergic illness
throughout the world. The major allergenic dust mites Dermatophagoides pteronyssinus …

Environmental variations induced by industrialization and climate change partially explain
the increase in prevalence and severity of allergic disease. One possible mechanism is the …

Allergic eye disease is common, yet often overlooked in North America. In the US, up to 40%
of the population is deemed to be affected and this number is growing. Symptoms and signs …

House dust mite (HDM) allergy belongs to the most important allergies and affects
approximately 65–130 million people worldwide. Additionally, untreated HDM allergy may …

Background House dust mites (HDM) are among the most important sources for airborne
allergens with high relevance for atopic diseases. Routine tests contain only 4 of 32 …

The prevalence of asthma has been rising steadily for several decades, and continues to be
a major public health and global economic burden due to both direct and indirect costs …

A large number of allergens have been discovered but we know little about their potential to
induce inflammation (allergenic activity) and symptoms. Nowadays, the clinical importance …

Background Asthma is a complex, multifactorial disease often linked with sensitization to
house dust mites (HDM). There is a subset of patients that does not respond to available …

FIG 1. Development of HDM allergen-specific IgE and IgG reactivities in the study population
during AIT.(A) Box plot representation of IgE (left) and IgG (right) levels to Der p 1, Der p 2 …