Polysaccharides, proteins, and synthetic polymers based multimodal hydrogels for various biomedical applications: A review

A Kumar, A Sood, G Agrawal, S Thakur… - International Journal of …, 2023 - Elsevier
Nature-derived or biologically encouraged hydrogels have attracted considerable interest in
numerous biomedical applications owing to their multidimensional utility and effectiveness …

[HTML][HTML] Injectable hydrogels in central nervous system: Unique and novel platforms for promoting extracellular matrix remodeling and tissue engineering

E Hasanzadeh, A Seifalian, A Mellati, J Saremi… - Materials Today Bio, 2023 - Elsevier
Repairing central nervous system (CNS) is difficult due to the inability of neurons to recover
after damage. A clinically acceptable treatment to promote CNS functional recovery and …

[HTML][HTML] Biomaterials to enhance stem cell transplantation

BN Kharbikar, P Mohindra, TA Desai - Cell Stem Cell, 2022 - cell.com
The successful transplantation of stem cells has the potential to transform regenerative
medicine approaches and open promising avenues to repair, replace, and regenerate …

Peptide‐based supramolecular therapeutics for fighting major diseases

Z Wang, H Luo, H Wang, M **ao, H Jia… - Advanced Functional …, 2024 - Wiley Online Library
Peptide‐based supramolecular therapeutics (PST) refer to those theranostic nanomedicines
based on peptide or peptide derivatives self‐assembly that are constructed in vitro or in vivo …

Biomaterials for cell transplantation

N Mitrousis, A Fokina, MS Shoichet - Nature Reviews Materials, 2018 - nature.com
Cell transplantation holds immense potential for reversing diseases that are currently
incurable and for regenerating tissues. However, poor cell survival, cell aggregation and …

Hydrogel oxygen reservoirs increase functional integration of neural stem cell grafts by meeting metabolic demands

Y Wang, ER Zoneff, JW Thomas, N Hong… - Nature …, 2023 - nature.com
Injectable biomimetic hydrogels have great potential for use in regenerative medicine as
cellular delivery vectors. However, they can suffer from issues relating to hypoxia, including …

Enhancing myocardial infarction treatment through bionic hydrogel-mediated spatial combination therapy via mtDNA-STING crosstalk modulation

Z Zheng, J Sun, J Wang, S He, Z Liu, J **e… - Journal of Controlled …, 2024 - Elsevier
Myocardial infarction (MI)-induced impaired cardiomyocyte (CM) mitochondrial function and
microenvironmental inflammatory cascades severely accelerate the progression of heart …

Applications of human brain organoids to clinical problems

HI Chen, H Song, G Ming - Developmental Dynamics, 2019 - Wiley Online Library
Brain organoids are an exciting new technology with the potential to significantly change
how diseases of the brain are understood and treated. These three‐dimensional neural …

Activity in grafted human iPS cell–derived cortical neurons integrated in stroke-injured rat brain regulates motor behavior

S Palma-Tortosa, D Tornero… - Proceedings of the …, 2020 - pnas.org
Stem cell transplantation can improve behavioral recovery after stroke in animal models but
whether stem cell–derived neurons become functionally integrated into stroke-injured brain …

Hypoxia-responsive calixarene-grafted self-assembled peptide hydrogel for inflammation suppression in ischemic stroke

W Zheng, SY Yao, H Hu, X Chen, Z Qian, W Liu, Y Zhu… - Nano Today, 2024 - Elsevier
Hypoxia is a significant characteristic of ischemic stroke. Recently, development of the
pathology of tissue injury and deployment of new hypoxia-responsive technologies provide …