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Neuromuscular junction transmission failure in aging and sarcopenia: The nexus of the neurological and muscular systems
Sarcopenia, or age-related decline in muscle form and function, exerts high personal,
societal, and economic burdens when untreated. Integrity and function of the neuromuscular …
societal, and economic burdens when untreated. Integrity and function of the neuromuscular …
State of knowledge on molecular adaptations to exercise in humans: historical perspectives and future directions
For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …
maintain, and restore healthy functioning of nearly every physiological system of the human …
Adaptive real-time identification of motor unit discharges from non-stationary high-density surface electromyographic signals
Objective: Estimation of the discharge pattern of motor units by electromyography (EMG)
decomposition has been applied for neurophysiologic investigations, clinical diagnosis, and …
decomposition has been applied for neurophysiologic investigations, clinical diagnosis, and …
Neuromuscular recruitment strategies of the vastus lateralis according to sex
Aim Despite males typically exhibiting greater muscle strength and fatigability than females,
it remains unclear if there are sex‐based differences in neuromuscular recruitment …
it remains unclear if there are sex‐based differences in neuromuscular recruitment …
Muscle-nerve communication and the molecular assessment of human skeletal muscle denervation with aging
Muscle fiber denervation is a major contributor to the decline in physical function observed
with aging. Denervation can occur through breakdown of the neuromuscular junctions (NMJ) …
with aging. Denervation can occur through breakdown of the neuromuscular junctions (NMJ) …
Ageing and exercise‐induced motor unit remodelling
A motor unit (MU) comprises the neuron cell body, its corresponding axon and each of the
muscle fibres it innervates. Many studies highlight age‐related reductions in the number of …
muscle fibres it innervates. Many studies highlight age‐related reductions in the number of …
Profiling age-related muscle weakness and wasting: neuromuscular junction transmission as a driver of age-related physical decline
Pathological age-related loss of skeletal muscle strength and mass contribute to impaired
physical function in older adults. Factors that promote the development of these conditions …
physical function in older adults. Factors that promote the development of these conditions …
Skeletal muscle dysfunction with advancing age
As a result of advances in medical treatments and associated policy over the last century, life
expectancy has risen substantially and continues to increase globally. However, the …
expectancy has risen substantially and continues to increase globally. However, the …
Neuromuscular dysfunction and exercise training in people with diabetic peripheral neuropathy: A narrative review
Diabetic peripheral neuropathy (DPN) is a common condition that is associated with
neuromuscular dysfunction and peripheral sensory impairment. These deficits predispose …
neuromuscular dysfunction and peripheral sensory impairment. These deficits predispose …
Neuroprotective effects of exercise on the aging human neuromuscular system
Human biological aging from maturity to senescence is associated with a gradual loss of
muscle mass and neuromuscular function. It is not until very old age (> 80 years) however …
muscle mass and neuromuscular function. It is not until very old age (> 80 years) however …