Voltage-Gated Proton Channels: Molecular Biology, Physiology, and Pathophysiology of the HV Family

TE DeCoursey - Physiological reviews, 2013 - journals.physiology.org
Voltage-gated proton channels (HV) are unique, in part because the ion they conduct is
unique. HV channels are perfectly selective for protons and have a very small unitary …

[HTML][HTML] Novel insights in hemodialysis: Most recent theories on membrane hemocompatibility improvement

A Mollahosseini, A Abdelrasoul - Biomedical Engineering Advances, 2022 - Elsevier
Kidney failure patients or patients with end-stage renal diseases (ESRD), need
hemodialysis (HD) as a life-sustaining service. However, the morbidity and mortality rates …

Surface chemistry-mediated modulation of adsorbed albumin folding state specifies nanocarrier clearance by distinct macrophage subsets

MP Vincent, S Bobbala, NB Karabin, M Frey… - Nature …, 2021 - nature.com
Controlling nanocarrier interactions with the immune system requires a thorough
understanding of the surface properties that modulate protein adsorption in biological fluids …

Molecular insight into human lysozyme and its ability to form amyloid fibrils in high concentrations of sodium dodecyl sulfate: a view from molecular dynamics …

M Jafari, F Mehrnejad - PLoS One, 2016 - journals.plos.org
Changes in the tertiary structure of proteins and the resultant fibrillary aggregation could
result in fatal heredity diseases, such as lysozyme systemic amyloidosis. Human lysozyme is …

Molecular self-assembly strategy for encapsulation of an amphipathic α-helical antimicrobial peptide into the different polymeric and copolymeric nanoparticles

M Jafari, F Doustdar, F Mehrnejad - Journal of chemical …, 2018 - ACS Publications
Encapsulation of peptide and protein-based drugs in polymeric nanoparticles is one of the
fundamental fields in controlled-release drug delivery systems. The molecular mechanisms …

Mechanistic insights into the urea-induced denaturation of kinase domain of human integrin linked kinase

SB Syed, FI Khan, SH Khan, S Srivastava… - International journal of …, 2018 - Elsevier
Abstract Integrin-linked kinase (ILK), a ubiquitously expressed intracellular Ser/Thr protein
kinase, plays a major role in the oncogenesis and tumour progression. The conformational …

Guanidinium–amino acid hydrogen-bonding interactions in protein crystal structures: implications for guanidinium-induced protein denaturation

I Negi, R Jangra, A Gharu, JF Trant… - Physical Chemistry …, 2023 - pubs.rsc.org
In the present work, 86 available high resolution X-ray structures of proteins that contain one
or more guanidinium ions (Gdm+) are analyzed for the distribution and nature of …

Effects of osmolytes on the helical conformation of model peptide: molecular dynamics simulation

F Mehrnejad, MM Ghahremanpour… - The Journal of …, 2011 - pubs.aip.org
Co-solvents such as glycerol and sorbitol are small organic molecules solvated in the
cellular solutions that can have profound effects on the protein structures. Here, the …

Insights into the Molecular-Level details of betaine interactions with Laccase under various thermal conditions

S Mojtabavi, M Jafari, N Samadi, F Mehrnejad… - Journal of Molecular …, 2021 - Elsevier
Laccase is a blue enzyme with a remarkable ability to eliminate environmental pollutants.
The use of the eco-friendly enzyme for removing ecological contaminants is extensive. In …

On the molecular mechanism of ion specific Hofmeister series

WJ **e, CW Liu, LJ Yang, YQ Gao - Science China Chemistry, 2014 - Springer
Hofmeister series ranks the ability of salt ions in influencing a variety of properties and
processes in aqueous solutions. In this review, we reexamine how these ions and some …