Non-coding RNAs in disease: from mechanisms to therapeutics
K Nemeth, R Bayraktar, M Ferracin… - Nature Reviews Genetics, 2024 - nature.com
Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
The emerging roles of circRNAs in cancer and oncology
Over the past decade, circular RNAs (circRNAs) have emerged as a large class of primarily
non-coding RNA molecules, many of which have key roles in cancer development and …
non-coding RNA molecules, many of which have key roles in cancer development and …
System-wide analysis of RNA and protein subcellular localization dynamics
Although the subcellular dynamics of RNA and proteins are key determinants of cell
homeostasis, their characterization is still challenging. Here we present an integrative …
homeostasis, their characterization is still challenging. Here we present an integrative …
miRNATissueAtlas2: an update to the human miRNA tissue atlas
Small non-coding RNAs (sncRNAs) are pervasive regulators of physiological and
pathological processes. We previously developed the human miRNA Tissue Atlas, detailing …
pathological processes. We previously developed the human miRNA Tissue Atlas, detailing …
Characterizing cellular heterogeneity in chromatin state with scCUT&Tag-pro
Technologies that profile chromatin modifications at single-cell resolution offer enormous
promise for functional genomic characterization, but the sparsity of the measurements and …
promise for functional genomic characterization, but the sparsity of the measurements and …
Long non-coding RNA PAARH promotes hepatocellular carcinoma progression and angiogenesis via upregulating HOTTIP and activating HIF-1α/VEGF signaling
H Wei, Z Xu, L Chen, Q Wei, Z Huang, G Liu, W Li… - Cell Death & …, 2022 - nature.com
Hepatocellular carcinoma (HCC) is one of the leading lethal malignancies and a
hypervascular tumor. Although some long non-coding RNAs (lncRNAs) have been revealed …
hypervascular tumor. Although some long non-coding RNAs (lncRNAs) have been revealed …
[كتاب][B] RNA, the epicenter of genetic information
The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …
Long non-coding RNAs: novel regulators of cellular physiology and function
Long non-coding RNAs were once considered as “junk” RNA produced by aberrant DNA
transcription. They are now understood to play central roles in diverse cellular processes …
transcription. They are now understood to play central roles in diverse cellular processes …
From junk to function: LncRNAs in CNS health and disease
Recent advances in RNA sequencing technologies helped to uncover the existence of tens
of thousands of long non-coding RNAs (lncRNAs) that arise from the dark matter of the …
of thousands of long non-coding RNAs (lncRNAs) that arise from the dark matter of the …
An ontology-based knowledge graph for representing interactions involving RNA molecules
The “RNA world” represents a novel frontier for the study of fundamental biological
processes and human diseases and is paving the way for the development of new drugs …
processes and human diseases and is paving the way for the development of new drugs …