Near-infrared luminescence high-contrast in vivo biomedical imaging

Y Chen, S Wang, F Zhang - Nature Reviews Bioengineering, 2023‏ - nature.com
Luminescence imaging in biomedical research has allowed new insights into the
architecture of pathological tissues, signalling networks and cell interactions, and is now …

Fluorescent probes for disease diagnosis

X Wang, Q Ding, RR Groleau, L Wu, Y Mao… - Chemical …, 2024‏ - ACS Publications
The identification and detection of disease-related biomarkers is essential for early clinical
diagnosis, evaluating disease progression, and for the development of therapeutics …

[HTML][HTML] Fluorescent-based nanosensors for selective detection of a wide range of biological macromolecules: A comprehensive review

S Sargazi, I Fatima, MH Kiani… - International Journal of …, 2022‏ - Elsevier
Thanks to their unique attributes, such as good sensitivity, selectivity, high surface-to-volume
ratio, and versatile optical and electronic properties, fluorescent-based bioprobes have been …

Bioactive NIR-II gold clusters for three-dimensional imaging and acute inflammation inhibition

H Ma, X Zhang, L Liu, Y Huang, S Sun, K Chen… - Science …, 2023‏ - science.org
Strong fluorescence and high catalytic activities cannot be achieved simultaneously due to
conflicts in free electron utilization, resulting in a lack of bioactivity of most near-infrared-II …

Design of NIR-II high performance organic small molecule fluorescent probes and summary of their biomedical applications

X Liu, B Yu, Y Shen, H Cong - Coordination Chemistry Reviews, 2022‏ - Elsevier
Near-infrared fluorescence imaging has gained a lot of attention in biomedicine by virtue of
its high sensitivity, high specificity, and many other advantages. Moreover, near-infrared II …

Donor/π‐Bridge manipulation for constructing a stable NIR‐II aggregation‐induced emission luminogen with balanced phototheranostic performance

D Yan, W **e, J Zhang, L Wang, D Wang… - Angewandte …, 2021‏ - Wiley Online Library
Owing to their versatile functionality and tunable energy dissipation, aggregation‐induced
emission luminogens (AIEgens) have emerged as a potential platform for multimodal …

Physiological principles underlying the kidney targeting of renal nanomedicines

Y Huang, X Ning, S Ahrari, Q Cai, N Rajora… - Nature Reviews …, 2024‏ - nature.com
Kidney disease affects more than 10% of the global population and is associated with
considerable morbidity and mortality, highlighting a need for new therapeutic options …

A water‐soluble AIEgen for noninvasive diagnosis of kidney fibrosis via SWIR fluorescence and photoacoustic imaging

D Yan, T Li, Y Yang, N Niu, D Wang, J Ge… - Advanced …, 2022‏ - Wiley Online Library
Early diagnosis of renal fibrosis is crucially significant on account of its worldwide prevalent
tendency. Optical imaging in the near‐infrared window has been recognized as an …

ROS/RNS and base dual activatable merocyanine‐based NIR‐II fluorescent molecular probe for in vivo biosensing

X Zhang, Y Chen, H He, S Wang, Z Lei… - Angewandte …, 2021‏ - Wiley Online Library
Inflammation usually results in high‐level reactive oxygen species (ROS) and reactive
nitrogen species (RNS) not only in acidic tissue but also in alkaline tissue. However …

Biomedical applications of NIR-II organic small molecule fluorescent probes in different organs

L Xu, Q Zhang, X Wang, W Lin - Coordination Chemistry Reviews, 2024‏ - Elsevier
The optimal functioning of body organs is fundamental to maintaining physiological
processes and bodily health. However, a myriad of factors, including inherent and …