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Gut microbiota in colorectal cancer development and therapy
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …
is its intimate association with the gut microbiota, which forms an essential part of the tumour …
Bacteria in cancer initiation, promotion and progression
G El Tekle, WS Garrett - Nature Reviews Cancer, 2023 - nature.com
Cancer cells originate from a series of acquired genetic mutations that can drive their
uncontrolled cell proliferation and immune evasion. Environmental factors, including the …
uncontrolled cell proliferation and immune evasion. Environmental factors, including the …
Tissue-resident Lachnospiraceae family bacteria protect against colorectal carcinogenesis by promoting tumor immune surveillance
X Zhang, D Yu, D Wu, X Gao, F Shao, M Zhao… - Cell host & …, 2023 - cell.com
The intestinal microbiota plays an important role in colorectal cancer (CRC) progression.
However, the effect of tissue-resident commensal bacteria on CRC immune surveillance …
However, the effect of tissue-resident commensal bacteria on CRC immune surveillance …
Understanding the role of the gut microbiome in gastrointestinal cancer: A review
D Ağagündüz, E Cocozza, Ö Cemali… - Frontiers in …, 2023 - frontiersin.org
Gastrointestinal cancer represents one of the most diagnosed types of cancer. Cancer is a
genetic and multifactorial disease, influenced by the host and environmental factors. It has …
genetic and multifactorial disease, influenced by the host and environmental factors. It has …
Oxidative stress, inflammation and colorectal cancer: an overview
Colorectal cancer (CRC) represents the second leading cause of cancer-related deaths
worldwide. The pathogenesis of CRC is a complex multistep process. Among other factors …
worldwide. The pathogenesis of CRC is a complex multistep process. Among other factors …
Promising dawn in tumor microenvironment therapy: engineering oral bacteria
Z Wang, W Sun, R Hua, Y Wang, Y Li… - International Journal of …, 2024 - nature.com
Despite decades of research, cancer continues to be a major global health concern. The
human mouth appears to be a multiplicity of local environments communicating with other …
human mouth appears to be a multiplicity of local environments communicating with other …
[HTML][HTML] Role and mechanism of gut microbiota in human disease
Y Chen, J Zhou, L Wang - Frontiers in cellular and infection …, 2021 - frontiersin.org
The human gut microbiome is a huge microbial community that plays an irreplaceable role
in human life. With the further development of research, the influence of intestinal flora on …
in human life. With the further development of research, the influence of intestinal flora on …
Fusobacterium nucleatum reduces METTL3-mediated m6A modification and contributes to colorectal cancer metastasis
S Chen, L Zhang, M Li, Y Zhang, M Sun, L Wang… - Nature …, 2022 - nature.com
Microbiota-host interactions play critical roles in colorectal cancer (CRC) progression,
however, the underlying mechanisms remain elusive. Here, we uncover that Fusobacterium …
however, the underlying mechanisms remain elusive. Here, we uncover that Fusobacterium …
The intestinal microbiota and colorectal cancer
The intestinal microbiota, composed of a large population of microorganisms, is often
considered a “forgotten organ” in human health and diseases. Increasing evidence indicates …
considered a “forgotten organ” in human health and diseases. Increasing evidence indicates …
Gut microbiota in colorectal cancer: mechanisms of action and clinical applications
Colorectal cancer (CRC) accounts for about 10% of all new cancer cases globally. Located
at close proximity to the colorectal epithelium, the gut microbiota comprises a large …
at close proximity to the colorectal epithelium, the gut microbiota comprises a large …