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Catalytic antibodies in healthy humans and patients with autoimmune and viral diseases
GA Nevinsky, VN Buneva - Journal of cellular and molecular …, 2003 - Wiley Online Library
Antibodies have been first characterized as proteins produced by the immune system solely
for binding other molecules, called antigens, with the goal of eliciting immune response. In …
for binding other molecules, called antigens, with the goal of eliciting immune response. In …
[HTML][HTML] Immunoglobulins with non-canonical functions in inflammatory and autoimmune disease states
EA Ermakov, GA Nevinsky, VN Buneva - International journal of molecular …, 2020 - mdpi.com
Immunoglobulins are known to combine various effector mechanisms of the adaptive and
the innate immune system. Classical immunoglobulin functions are associated with antigen …
the innate immune system. Classical immunoglobulin functions are associated with antigen …
Hydrolysis of myelin basic protein by polyclonal catalytic IgGs from the sera of patients with multiple sclerosis
DI Polosukhina, TG Kanyshkova… - Journal of cellular …, 2004 - Wiley Online Library
Various catalytic antibodies or abzymes have been detected recently in the sera of patients
with several autoimmune pathologies, where their presence is most probably associated …
with several autoimmune pathologies, where their presence is most probably associated …
Affinity and catalytic heterogeneity and metal‐dependence of polyclonal myelin basic protein‐hydrolyzing IgGs from sera of patients with systemic lupus …
AM Bezuglova, LP Konenkova… - Journal of Molecular …, 2011 - Wiley Online Library
It was shown using enzyme‐linked immunosorbent assay (ELISA) that titers of antibodies
against human myelin basic protein (hMBP) in systemic lupus erythematosus (SLE) patients …
against human myelin basic protein (hMBP) in systemic lupus erythematosus (SLE) patients …
Autoimmune processes in multiple sclerosis: Production of harmful catalytic antibodies associated with significant changes in the hematopoietic stem cell …
GA Nevinsky - Trending Topics in Multiple Sclerosis, 2016 - books.google.com
Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system. MS
pathogenesis is not clear. Destruction of myelin by inflammation caused by autoimmune …
pathogenesis is not clear. Destruction of myelin by inflammation caused by autoimmune …
Metal-dependent hydrolysis of myelin basic protein by IgGs from the sera of patients with multiple sclerosis
IP Dar'ya, GK Tat'yana, BM Doronin, OB Tyshkevich… - Immunology letters, 2006 - Elsevier
Homogeneous IgG fractions were obtained by chromatography of the sera of patients with
multiple sclerosis (MS) on Protein G-Sepharose under conditions that remove non …
multiple sclerosis (MS) on Protein G-Sepharose under conditions that remove non …
Hydrolysis of myelin basic protein by IgM and IgA antibodies from the sera of patients with multiple sclerosis
I Dar'ya, VN Buneva1CDF… - … medical journal of …, 2005 - medscimonit.com
Background: The presence of abzymes (Abzs) in human sera is a specific feature of different
autoimmune pathologies. We have shown that IgGs of patients with multiple sclerosis (MS) …
autoimmune pathologies. We have shown that IgGs of patients with multiple sclerosis (MS) …
Natural catalytic antibodies in norm and in HIV-infected patients
GA Nevinsky - Understanding HIV/AIDS Management and Care …, 2011 - books.google.com
Antibodies (Abs) have been first characterized as proteins which are produced by the
immune system and have a sole function of binding other molecules, called antigens, with …
immune system and have a sole function of binding other molecules, called antigens, with …
Catalytic antibodies in norm and systemic lupus erythematosus
GA Nevinsky - Lupus; Khan, WA, Ed.; InTech: Rijeka, Croatia, 2017 - books.google.com
Systemic lupus erythematosus (SLE) is known as a systemic polyethiologic diffuse
autoimmune disease characterized by connective tissue disorganization and the paramount …
autoimmune disease characterized by connective tissue disorganization and the paramount …
Physiological IgM class catalytic antibodies selective for transthyretin amyloid
SA Planque, Y Nishiyama, M Hara, S Sonoda… - Journal of Biological …, 2014 - jbc.org
Peptide bond-hydrolyzing catalytic antibodies (catabodies) could degrade toxic proteins, but
acquired immunity principles have not provided evidence for beneficial catabodies …
acquired immunity principles have not provided evidence for beneficial catabodies …