Transcriptional enhancers and their communication with gene promoters

H Ray-Jones, M Spivakov - Cellular and Molecular Life Sciences, 2021 - Springer
Transcriptional enhancers play a key role in the initiation and maintenance of gene
expression programmes, particularly in metazoa. How these elements control their target …

Applications of CRISPR-Cas in bioengineering, biotechnology, and translational research

CH Lau - The CRISPR journal, 2018 - liebertpub.com
CRISPR technology is rapidly evolving, and the scope of CRISPR applications is constantly
expanding. CRISPR was originally employed for genome editing. Its application was then …

Chromatin manipulation and editing: challenges, new technologies and their use in plants

K Fal, D Tomkova, G Vachon, ME Chaboute… - International Journal of …, 2021 - mdpi.com
An ongoing challenge in functional epigenomics is to develop tools for precise manipulation
of epigenetic marks. These tools would allow moving from correlation-based to causal …

SATB1 chromatin loops regulate Megakaryocyte/Erythroid Progenitor Expansion by facilitating HSP70 and GATA1 induction

MC Wilkes, HD Chae, V Scanlon, AM Cepika… - Stem Cells, 2023 - academic.oup.com
Diamond Blackfan anemia (DBA) is an inherited bone marrow failure syndrome associated
with severe anemia, congenital malformations, and an increased risk of develo** cancer …

UBA1-CDK16: A Sex-Specific Chimeric RNA and Its Role in Immune Sexual Dimorphism

X Shi, L Facemire, S Singh, S Kumar, R Cornelison… - bioRxiv, 2024 - biorxiv.org
RNA processing mechanisms, such as alternative splicing and RNA editing, have been
recognized as critical means to expand the transcriptome. Chimeric RNAs formed by …