The potential of metabolomics in biomedical applications
The metabolome offers a dynamic, comprehensive, and precise picture of the phenotype.
Current high-throughput technologies have allowed the discovery of relevant metabolites …
Current high-throughput technologies have allowed the discovery of relevant metabolites …
Cardiovascular metabolomics
Disturbances in cardiac metabolism underlie most cardiovascular diseases. Metabolomics,
one of the newer omics technologies, has emerged as a powerful tool for defining changes …
one of the newer omics technologies, has emerged as a powerful tool for defining changes …
Chemometrics in metabolomics—a review in human disease diagnosis
R Madsen, T Lundstedt, J Trygg - Analytica chimica acta, 2010 - Elsevier
Metabolomics is a post genomic research field concerned with develo** methods for
analysis of low molecular weight compounds in biological systems, such as cells, organs or …
analysis of low molecular weight compounds in biological systems, such as cells, organs or …
Systems proteomics of liver mitochondria function
INTRODUCTION Over the past two decades, continuous improvements in “omics”
technologies have driven an ever-greater capacity to define the relationships between …
technologies have driven an ever-greater capacity to define the relationships between …
Combined metabolomic and proteomic analysis of human atrial fibrillation
Objectives: We sought to decipher metabolic processes servicing the increased energy
demand during persistent atrial fibrillation (AF) and to ascertain whether metabolic …
demand during persistent atrial fibrillation (AF) and to ascertain whether metabolic …
Diagnosis and monitoring of abdominal aortic aneurysm: current status and future prospects
Abdominal aortic aneurysm (AAA) remains an important cause of morbidity and mortality in
elderly men, and prevalence is predicted to increase in parallel with a global aging …
elderly men, and prevalence is predicted to increase in parallel with a global aging …
Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques
Background—Microparticles (MPs) with procoagulant activity are present in human
atherosclerosis, but no detailed information is available on their composition. Methods and …
atherosclerosis, but no detailed information is available on their composition. Methods and …
Proteomics identifies thymidine phosphorylase as a key regulator of the angiogenic potential of colony-forming units and endothelial progenitor cell cultures
Endothelial progenitor cell (EPC) cultures and colony-forming units (CFUs) have been
extensively studied for their therapeutic and diagnostic potential. Recent data suggest a role …
extensively studied for their therapeutic and diagnostic potential. Recent data suggest a role …
Proteomics: from single molecules to biological pathways
The conventional reductionist approach to cardiovascular research investigates individual
candidate factors or linear signalling pathways but ignores more complex interactions in …
candidate factors or linear signalling pathways but ignores more complex interactions in …
Single-platform 'multi-omic'profiling: unified mass spectrometry and computational workflows for integrative proteomics–metabolomics analysis
The objective of omics studies is to globally measure the different classes of cellular
biomolecules present in a biological specimen (eg proteins, metabolites) as accurately as …
biomolecules present in a biological specimen (eg proteins, metabolites) as accurately as …