Annexin animal models—from fundamental principles to translational research

T Grewal, C Rentero, C Enrich, M Wahba… - International Journal of …, 2021 - mdpi.com
Routine manipulation of the mouse genome has become a landmark in biomedical
research. Traits that are only associated with advanced developmental stages can now be …

Metalloproteinases and their roles in human cancer

R Roy, G Morad, A Jedinak… - The Anatomical Record, 2020 - Wiley Online Library
It is now widely appreciated that members of the matrix metalloproteinase (MMP) family of
enzymes play a key role in cancer development and progression along with many of the …

Identification of proteins associated with development of metastasis from cutaneous squamous cell carcinomas (cSCCs) via proteomic analysis of primary cSCCs

A Shapanis, C Lai, S Smith, G Coltart… - British Journal of …, 2021 - academic.oup.com
Background Cutaneous squamous cell carcinoma (cSCC) is one of the most common
cancers capable of metastasizing. Proteomic analysis of cSCCs can provide insight into the …

The relevance, predictability, and utility of annexin A5 for human physiopathology

J **g - International Journal of Molecular Sciences, 2024 - mdpi.com
As an important functional protein molecule in the human body, human annexin A5
(hAnxA5) is widely found in human cells and body fluids. hAnxA5, the smallest type of …

Tissue-based proteomic profiling in patients with hyperplasia and endometrial cancer

K Akkour, IO Alanazi, AA Alfadda, H Alhalal, A Masood… - Cells, 2022 - mdpi.com
Uterine cancers are among the most prevalent gynecological malignancies, and
endometrial cancer (EC) is the most common in this group. This study used tissue-based …

Potential prognostic and therapeutic value of ANXA8 in renal cell carcinoma: based on the comprehensive analysis of annexins family

LH Wang, B Cao, YL Li, BP Qiao - BMC cancer, 2023 - Springer
Background Annexins are a family of proteins involved in a wide variety of cellular
processes such as inflammation, proliferation, differentiation, apoptosis, migration and …

[HTML][HTML] The role of ANXA5 in DBP-induced oxidative stress through ERK/Nrf2 pathway

L Zhang, Z Qin, R Li, S Wang, W Wang, M Tang… - Environmental …, 2019 - Elsevier
Abstract Di-N-butylphthalate (DBP) have given rise to more and more attention due to its
unique endocrine toxicity to male reproductive system. Our previous studies have …

HAPLN3 inhibits apoptosis and promotes EMT of clear cell renal cell carcinoma via ERK and Bcl-2 signal pathways

Y Ding, S **ong, X Chen, Q Pan, J Fan… - Journal of Cancer …, 2023 - Springer
Hyaluronan and proteoglycan link protein 3 (HAPLN3) is a member of the hyaluronan and
proteoglycan link protein family expressed in the extracellular matrix closely associated with …

Calcium relieves fluoride-induced bone damage through the PI3K/AKT pathway

J Wang, H Xu, X Cheng, J Yang, Z Yan, H Ma… - Food & function, 2020 - pubs.rsc.org
Bone is the main target of fluorosis, and it has been perfectly elaborated that a moderate
dosage of calcium (Ca) can alleviate bone fluorosis. However, whether Ca can alleviate …

The potential role of exosomal proteins in prostate cancer

S Feng, K Lou, X Zou, J Zou, G Zhang - Frontiers in Oncology, 2022 - frontiersin.org
Prostate cancer is the most prevalent malignant tumor in men across developed countries.
Traditional diagnostic and therapeutic methods for this tumor have become increasingly …