[HTML][HTML] Lipids and polymers in pharmaceutical technology: Lifelong companions

J Siepmann, A Faham, SD Clas, BJ Boyd… - International journal of …, 2019 - Elsevier
In pharmaceutical technology, lipids and polymers are considered pillar excipients for the
fabrication of most dosage forms, irrespective of the administration route. They play various …

Spotlight on 17‐AAG as an Hsp90 inhibitor for molecular targeted cancer treatment

S Talaei, H Mellatyar, A Asadi… - Chemical biology & …, 2019 - Wiley Online Library
Hsp90 is a ubiquitous chaperone with important roles in the organization and maturation of
client proteins that are involved in the progression and survival of cancer cells. Multiple …

[HTML][HTML] Autophagy modulators: mechanistic aspects and drug delivery systems

S Tavakol, M Ashrafizadeh, S Deng, M Azarian… - Biomolecules, 2019 - mdpi.com
Autophagy modulation is considered to be a promising programmed cell death mechanism
to prevent and cure a great number of disorders and diseases. The crucial step in designing …

[LIBRO][B] Encyclopedia of Polymer Applications, 3 Volume Set

M Mishra - 2018 - taylorfrancis.com
Undoubtedly the applications of polymers are rapidly evolving. Technology is continually
changing and quickly advancing as polymers are needed to solve a variety of day-to-day …

Production of paclitaxel-loaded PEG-b-PLA micelles using PEG for drug loading and freeze-drying

M Rasoulianboroujeni, L Repp, HJ Lee… - Journal of Controlled …, 2022 - Elsevier
A new approach named PEG-assist is introduced for the production of drug-loaded
polymeric micelles. The method is based on the use of PEG as the non-selective solvent for …

Codelivery for paclitaxel and Bcl‐2 conversion gene by PHB‐PDMAEMA amphiphilic cationic copolymer for effective drug resistant cancer therapy

X Wang, SS Liow, Q Wu, C Li, C Owh… - Macromolecular …, 2017 - Wiley Online Library
Antiapoptotic Bcl‐2 protein's upregulated expression is a key reason for drug resistance
leading to failure of chemotherapy. In this report, a series of biocompatible amphiphilic …

Unforeseen consequences of synergizing PEGylated rapamycin and quercetin in angiogenesis and metastasis inhibition: Turning failure into benefit

M Al Amili, C Zou, Y **a, P Zeng, Y Qi, Y Shen… - Chemical Engineering …, 2023 - Elsevier
Cancer continues to be a significant health hazard to the patient's body around the globe,
with more than 19 million incidents in 2020 worldwide, according to the world health …

Heat shock proteins and cancer: How can nanomedicine be harnessed?

F Sauvage, S Messaoudi, E Fattal, G Barratt… - Journal of Controlled …, 2017 - Elsevier
Heat shock protein (hsp90) is an interesting target for cancer therapy because it is involved
in the folding and stabilization of numerous proteins, including many that contribute to the …

Radiation-assisted strategies provide new perspectives to improve the nanoparticle delivery to tumor

D Zhang, J He, M Zhou - Advanced Drug Delivery Reviews, 2023 - Elsevier
Nanoparticles (NPs), with advantages in tumor targeting, have been extensively developed
for anticancer treatment. However, the delivery efficacy of NPs tends to be heterogeneous in …

Thermoresponsive Supramolecular Chemotherapy by “V”‐Shaped Armed β‐Cyclodextrin Star Polymer to Overcome Drug Resistance

X Fan, H Cheng, X Wang, E Ye, XJ Loh… - Advanced healthcare …, 2018 - Wiley Online Library
Pump mediated drug efflux is the key reason to result in the failure of chemotherapy. Herein,
a novel star polymer β‐CD‐v‐(PEG‐β‐PNIPAAm) 7 consisting of a β‐CD core, grafted with …