Model systems for regeneration: salamanders

A Joven, A Elewa, A Simon - Development, 2019‏ - journals.biologists.com
Salamanders have been hailed as champions of regeneration, exhibiting a remarkable
ability to regrow tissues, organs and even whole body parts, eg their limbs. As such …

[HTML][HTML] Neural tissue engineering with structured hydrogels in CNS models and therapies

J George, CC Hsu, LTB Nguyen, H Ye, Z Cui - Biotechnology advances, 2020‏ - Elsevier
The development of techniques to create and use multiphase microstructured hydrogels
(granular hydrogels or microgels) has enabled the generation of cultures with more …

Single-cell Stereo-seq reveals induced progenitor cells involved in axolotl brain regeneration

X Wei, S Fu, H Li, Y Liu, S Wang, W Feng, Y Yang… - Science, 2022‏ - science.org
The molecular mechanism underlying brain regeneration in vertebrates remains elusive. We
performed spatial enhanced resolution omics sequencing (Stereo-seq) to capture spatially …

[کتاب][B] Meandering sobriety

QH Vuong - 2023‏ - books.google.com
(Third edition, with additions) Thinking is a fundamental activity of our species–those that
give names to other creatures and call themselves humans. Textbooks tell us that there is …

Single-cell analyses of axolotl telencephalon organization, neurogenesis, and regeneration

K Lust, A Maynard, T Gomes, JS Fleck, JG Camp… - Science, 2022‏ - science.org
Salamanders are tetrapod models to study brain organization and regeneration; however,
the identity and evolutionary conservation of brain cell types are largely unknown. We …

A versatile depigmentation, clearing, and labeling method for exploring nervous system diversity

M Pende, K Vadiwala, H Schmidbaur… - Science …, 2020‏ - science.org
Tissue clearing combined with deep imaging has emerged as a powerful alternative to
classical histological techniques. Whereas current techniques have been optimized for …

Single cell sequencing of radial glia progeny reveals the diversity of newborn neurons in the adult zebrafish brain

C Lange, F Rost, A Machate, S Reinhardt… - …, 2020‏ - journals.biologists.com
Zebrafish display widespread and pronounced adult neurogenesis, which is fundamental for
their regeneration capability after central nervous system injury. However, the cellular …

Spateo: multidimensional spatiotemporal modeling of single-cell spatial transcriptomics

X Qiu, DY Zhu, J Yao, Z **g, L Zuo, M Wang, KH Min… - BioRxiv, 2022‏ - biorxiv.org
Cells do not live in a vacuum, but in a milieu defined by cell–cell communication that can be
measured via emerging high-resolution spatial transcriptomics approaches. However …

Visceral adiposity, inflammation, and hippocampal function in obesity

AM Stranahan - Neuropharmacology, 2022‏ - Elsevier
The 'apple-shaped'anatomical pattern that accompanies visceral adiposity increases risk for
multiple chronic diseases, including conditions that impact the brain, such as diabetes and …

Quiescent neural stem cells for brain repair and regeneration: lessons from model systems

L Otsuki, AH Brand - Trends in Neurosciences, 2020‏ - cell.com
Neural stem cells (NSCs) are multipotent progenitors that are responsible for producing all
of the neurons and macroglia in the nervous system. In adult mammals, NSCs reside …