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Molecular anatomy and pathogenic actions of Helicobacter pylori CagA that underpin gastric carcinogenesis
Chronic infection with Helicobacter pylori cagA-positive strains is the strongest risk factor for
gastric cancer. The cagA gene product, CagA, is delivered into gastric epithelial cells via the …
gastric cancer. The cagA gene product, CagA, is delivered into gastric epithelial cells via the …
Structure and function of Helicobacter pylori CagA, the first-identified bacterial protein involved in human cancer
M Hatakeyama - Proceedings of the Japan Academy, Series B, 2017 - jstage.jst.go.jp
Chronic infection with Helicobacter pylori cagA-positive strains is the strongest risk factor of
gastric cancer. The cagA gene-encoded CagA protein is delivered into gastric epithelial …
gastric cancer. The cagA gene-encoded CagA protein is delivered into gastric epithelial …
Helicobacter pylori: gastric cancer and beyond
DB Polk, RM Peek Jr - Nature reviews cancer, 2010 - nature.com
Helicobacter pylori is the dominant species of the human gastric microbiome, and
colonization causes a persistent inflammatory response. H. pylori-induced gastritis is the …
colonization causes a persistent inflammatory response. H. pylori-induced gastritis is the …
The Helicobacter pylori cag pathogenicity island as a determinant of gastric cancer risk
Helicobacter pylori strains can be broadly classified into two groups based on whether they
contain or lack a chromosomal region known as the cag pathogenicity island (cag PAI) …
contain or lack a chromosomal region known as the cag pathogenicity island (cag PAI) …
Pathogenesis of Helicobacter pylori Infection
Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …
most successful human pathogens, as over half of the world's population is colonized with …
Mechanisms of disease: Helicobacter pylori virulence factors
Helicobacter pylori plays an essential role in the development of various gastroduodenal
diseases; however, only a small proportion of people infected with H. pylori develop these …
diseases; however, only a small proportion of people infected with H. pylori develop these …
Helicobacter pylori in health and disease
Helicobacter pylori is highly adapted for colonization of the human stomach and is present in
about half of the human population. When present, H pylori is usually the numerically …
about half of the human population. When present, H pylori is usually the numerically …
[HTML][HTML] Helicobacter pylori persistence: biology and disease
Helicobacter pylori are bacteria that have coevolved with humans to be transmitted from
person to person and to persistently colonize the stomach. Their population structure is a …
person to person and to persistently colonize the stomach. Their population structure is a …
Pathogenicity islands in bacterial pathogenesis
In this review, we focus on a group of mobile genetic elements designated pathogenicity
islands (PAI). These elements play a pivotal role in the virulence of bacterial pathogens of …
islands (PAI). These elements play a pivotal role in the virulence of bacterial pathogens of …
Vacuolating cytotoxin A (VacA), a key toxin for Helicobacter pylori pathogenesis
SL Palframan, T Kwok, K Gabriel - Frontiers in cellular and infection …, 2012 - frontiersin.org
More than 50% of the world's population is infected with Helicobacter pylori (H. pylori).
Chronic infection with this Gram-negative pathogen is associated with the development of …
Chronic infection with this Gram-negative pathogen is associated with the development of …