Fibroblast and myofibroblast activation in normal tissue repair and fibrosis

FS Younesi, AE Miller, TH Barker, FMV Rossi… - … Reviews Molecular Cell …, 2024 - nature.com
The term 'fibroblast'often serves as a catch-all for a diverse array of mesenchymal cells,
including perivascular cells, stromal progenitor cells and bona fide fibroblasts. Although …

Linking cell mechanical memory and cancer metastasis

E Cambria, MF Coughlin, MA Floryan… - Nature Reviews …, 2024 - nature.com
Metastasis causes most cancer-related deaths; however, the efficacy of anti-metastatic drugs
is limited by incomplete understanding of the biological mechanisms that drive metastasis …

A review on the design of hydrogels with different stiffness and their effects on tissue repair

T Luo, B Tan, L Zhu, Y Wang, J Liao - Frontiers in bioengineering and …, 2022 - frontiersin.org
Tissue repair after trauma and infection has always been a difficult problem in regenerative
medicine. Hydrogels have become one of the most important scaffolds for tissue …

Light-based 3D bioprinting of bone tissue scaffolds with tunable mechanical properties and architecture from photocurable silk fibroin

M Rajput, P Mondal, P Yadav, K Chatterjee - International Journal of …, 2022 - Elsevier
Abstract Three-dimensional (3D) bioprinting based on digital light processing (DLP) offers
unique opportunities to prepare scaffolds that mimic the architecture and biomechanical …

[HTML][HTML] Biophysical regulation of cell behavior—cross talk between substrate stiffness and nanotopography

Y Yang, K Wang, X Gu, KW Leong - Engineering, 2017 - Elsevier
The stiffness and nanotopographical characteristics of the extracellular matrix (ECM)
influence numerous developmental, physiological, and pathological processes in vivo …

Effects of substrate stiffness and cell-cell contact on mesenchymal stem cell differentiation

AS Mao, JW Shin, DJ Mooney - Biomaterials, 2016 - Elsevier
The mechanical properties of the microenvironment and direct contact-mediated cell-cell
interactions are two variables known to be important in the determination of stem cell …

Hydrogels for bone organoid construction: From a materiobiological perspective

S Wu, X Wu, X Wang, J Su - Journal of materials science & technology, 2023 - Elsevier
Bone organoids, which simulate and construct special organs in vitro with complex
biological functions based on tissue engineering technology, provide dramatically realistic …

Stem cell mechanobiology and the role of biomaterials in governing mechanotransduction and matrix production for tissue regeneration

SM Naqvi, LM McNamara - Frontiers in bioengineering and …, 2020 - frontiersin.org
Mechanobiology has underpinned many scientific advances in understanding how
biophysical and biomechanical cues regulate cell behavior by identifying mechanosensitive …

Microfluidic skin‐on‐a‐chip models: Toward biomimetic artificial skin

E Sutterby, P Thurgood, S Baratchi, K Khoshmanesh… - Small, 2020 - Wiley Online Library
The role of skin in the human body is indispensable, serving as a barrier, moderating
homeostatic balance, and representing a pronounced endpoint for cosmetics and …

Mechanics of intact bone marrow

LE Jansen, NP Birch, JD Schiffman, AJ Crosby… - Journal of the …, 2015 - Elsevier
The current knowledge of bone marrow mechanics is limited to its viscous properties,
neglecting the elastic contribution of the extracellular matrix. To get a more complete view of …