Frailty is a multiply determined, age-related state of increased risk for adverse health
outcomes. We review how the degree of frailty conditions the development of late-life …

Frailty is an age-related clinical condition characterised by an increased susceptibility to
stressors and an elevated risk of adverse outcomes such as mortality. In the light of global …

Objective This study aimed to determine the comparative effectiveness of interventions in
treatment of sarcopenia. The primary outcome was the measure of treatment effect on …

Background Frailty endangers the health of older adults. Furthermore, the prevalence of
frailty continues to increase as the global population ageing. Objective To update evidence …

Introduction The benefits of physical activity for people living with long-term conditions
(LTCs) are well established. However, the risks of physical activity are less well …

Background One of the most challenging issues for the elderly population is the clinical state
of frailty. Frailty is defined as a cumulative decline across psychological, physical, and social …

Frailty is characterized by diminished resilience to stressor events. It is associated with
adverse future health outcomes and impedes healthy aging. The circadian system …

The aging process in an older adult is driven by multidimensional inputs that contribute to an
individual's overall progressive decline and ultimately death. These inputs span biological …

The management of frail older people is a key component of aged care. There has been a
plethora of tools developed for the diagnosis and screening of frailty. Some of these tools …

Endothelial dysfunction is a key hallmark of hypertension, which is a leading risk factor for
cognitive decline in older adults with or without frailty. Similarly, hyperglycemia is known to …