Nickel: Human health and environmental toxicology

G Genchi, A Carocci, G Lauria, MS Sinicropi… - International journal of …, 2020‏ - mdpi.com
Nickel is a transition element extensively distributed in the environment, air, water, and soil.
It may derive from natural sources and anthropogenic activity. Although nickel is ubiquitous …

Nutritional implications of ginger: chemistry, biological activities and signaling pathways

R Kiyama - The Journal of nutritional biochemistry, 2020‏ - Elsevier
Abstract Ginger (Zingiber officinale Roscoe) has been used as a food, spice, supplement
and flavoring agent and in traditional medicines due to its beneficial characteristics such as …

Role of epigenetics in biology and human diseases

A Moosavi, AM Ardekani - Iranian biomedical journal, 2016‏ - pmc.ncbi.nlm.nih.gov
For a long time, scientists have tried to describe disorders just by genetic or environmental
factors. However, the role of epigenetics in human diseases has been considered from a …

MicroRNA epigenetic signatures in human disease

K Piletič, T Kunej - Archives of toxicology, 2016‏ - Springer
MicroRNAs (miRNAs) are short non-coding RNAs that act as important regulators of gene
expression as part of the epigenetic machinery. In addition to posttranscriptional gene …

[HTML][HTML] MicroRNAs and spermatogenesis

N Kotaja - Fertility and sterility, 2014‏ - Elsevier
In mammals, male gametes are produced inside the testis by spermatogenesis, which has
three phases: mitotic proliferation of spermatogonia, meiosis of spermatocytes, and haploid …

Dysregulation of microRNAs in autoimmune diseases: Pathogenesis, biomarkers and potential therapeutic targets

H Long, X Wang, Y Chen, L Wang, M Zhao, Q Lu - Cancer letters, 2018‏ - Elsevier
MicroRNAs (miRNAs) are small, single-stranded, endogenous non-coding RNAs that
repress the expression of target genes via post-transcriptional mechanisms. Due to their …

New viruses for cancer therapy: meeting clinical needs

TS Miest, R Cattaneo - Nature reviews microbiology, 2014‏ - nature.com
Early-stage clinical trials of oncolytic virotherapy have reported the safety of several virus
platforms, and viruses from three families have progressed to advanced efficacy trials. In …

MicroRNA in glioblastoma: an overview

B Banelli, A Forlani, G Allemanni… - … journal of genomics, 2017‏ - Wiley Online Library
Glioblastoma is the most aggressive brain tumor and, even with the current multimodal
therapy, is an invariably lethal cancer with a life expectancy that depends on the tumor …

Targeting epigenetics and non-coding RNAs in atherosclerosis: from mechanisms to therapeutics

S Xu, D Kamato, PJ Little, S Nakagawa… - Pharmacology & …, 2019‏ - Elsevier
Atherosclerosis, the principal cause of cardiovascular death worldwide, is a pathological
disease characterized by fibro-proliferation, chronic inflammation, lipid accumulation, and …

Stress-induced changes in miRNA biogenesis and functioning

M Olejniczak, A Kotowska-Zimmer… - Cellular and molecular life …, 2018‏ - Springer
MicroRNAs (miRNAs) are small, noncoding RNAs that play key roles in the regulation of
cellular homeostasis in eukaryotic organisms. There is emerging evidence that some of …