Tumor-associated macrophages in cancer: recent advancements in cancer nanoimmunotherapies

N Kumari, SH Choi - Journal of Experimental & Clinical Cancer Research, 2022 - Springer
Cancer immunotherapy has emerged as a novel cancer treatment, although recent
immunotherapy trials have produced suboptimal outcomes, with durable responses seen …

Tumor‐microenvironment‐responsive nanomedicine for enhanced cancer immunotherapy

S Peng, F **ao, M Chen, H Gao - Advanced Science, 2022 - Wiley Online Library
The past decades have witnessed great progress in cancer immunotherapy, which has
profoundly revolutionized oncology, whereas low patient response rates and potential …

Engineering macrophages for cancer immunotherapy and drug delivery

Y **a, L Rao, H Yao, Z Wang, P Ning… - Advanced …, 2020 - Wiley Online Library
Macrophages play an important role in cancer development and metastasis.
Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2 …

Tailoring materials for modulation of macrophage fate

J Li, X Jiang, H Li, M Gelinsky, Z Gu - Advanced Materials, 2021 - Wiley Online Library
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …

Second near‐infrared photothermal semiconducting polymer nanoadjuvant for enhanced cancer immunotherapy

J Li, X Yu, Y Jiang, S He, Y Zhang, Y Luo… - Advanced …, 2021 - Wiley Online Library
Immunotherapy has offered new treatment options for cancer; however, the therapeutic
benefits are often modest and desired to be improved. A semiconducting polymer …

A review on nano-based drug delivery system for cancer chemoimmunotherapy

W Mu, Q Chu, Y Liu, N Zhang - Nano-Micro Letters, 2020 - Springer
Although notable progress has been made on novel cancer treatments, the overall survival
rate and therapeutic effects are still unsatisfactory for cancer patients …

Nano-enhanced immunotherapy: Targeting the immunosuppressive tumor microenvironment

Y **, Y Huang, H Ren, H Huang, C Lai, W Wang… - Biomaterials, 2024 - Elsevier
The tumor microenvironment (TME), which is mostly composed of tumor cells, immune cells,
signaling molecules, stromal tissue, and the vascular system, is an integrated system that is …

Biomaterial-assisted targeted modulation of immune cells in cancer treatment

H Wang, DJ Mooney - Nature materials, 2018 - nature.com
The past decade has witnessed the accelerating development of immunotherapies for
cancer treatment. Immune checkpoint blockade therapies and chimeric antigen receptor …

Pre-metastatic niche: formation, characteristics and therapeutic implication

Y Wang, J Jia, F Wang, Y Fang, Y Yang… - … and Targeted Therapy, 2024 - nature.com
Distant metastasis is a primary cause of mortality and contributes to poor surgical outcomes
in cancer patients. Before the development of organ-specific metastasis, the formation of a …

Engineering endogenous tumor‐associated macrophage‐targeted biomimetic nano‐RBC to Reprogram tumor immunosuppressive microenvironment for enhanced …

Y Wang, J Yu, Z Luo, Q Shi, G Liu, F Wu… - Advanced …, 2021 - Wiley Online Library
Immunotherapy has shown encouraging results in various cancers, but the response rates
are relatively low due to the complex tumor immunosuppressive microenvironment (TIME) …