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Tumor-associated macrophages in cancer: recent advancements in cancer nanoimmunotherapies
Cancer immunotherapy has emerged as a novel cancer treatment, although recent
immunotherapy trials have produced suboptimal outcomes, with durable responses seen …
immunotherapy trials have produced suboptimal outcomes, with durable responses seen …
Tumor‐microenvironment‐responsive nanomedicine for enhanced cancer immunotherapy
The past decades have witnessed great progress in cancer immunotherapy, which has
profoundly revolutionized oncology, whereas low patient response rates and potential …
profoundly revolutionized oncology, whereas low patient response rates and potential …
Engineering macrophages for cancer immunotherapy and drug delivery
Macrophages play an important role in cancer development and metastasis.
Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2 …
Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2 …
Tailoring materials for modulation of macrophage fate
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
Second near‐infrared photothermal semiconducting polymer nanoadjuvant for enhanced cancer immunotherapy
Immunotherapy has offered new treatment options for cancer; however, the therapeutic
benefits are often modest and desired to be improved. A semiconducting polymer …
benefits are often modest and desired to be improved. A semiconducting polymer …
A review on nano-based drug delivery system for cancer chemoimmunotherapy
W Mu, Q Chu, Y Liu, N Zhang - Nano-Micro Letters, 2020 - Springer
Although notable progress has been made on novel cancer treatments, the overall survival
rate and therapeutic effects are still unsatisfactory for cancer patients …
rate and therapeutic effects are still unsatisfactory for cancer patients …
Nano-enhanced immunotherapy: Targeting the immunosuppressive tumor microenvironment
Y **, Y Huang, H Ren, H Huang, C Lai, W Wang… - Biomaterials, 2024 - Elsevier
The tumor microenvironment (TME), which is mostly composed of tumor cells, immune cells,
signaling molecules, stromal tissue, and the vascular system, is an integrated system that is …
signaling molecules, stromal tissue, and the vascular system, is an integrated system that is …
Biomaterial-assisted targeted modulation of immune cells in cancer treatment
The past decade has witnessed the accelerating development of immunotherapies for
cancer treatment. Immune checkpoint blockade therapies and chimeric antigen receptor …
cancer treatment. Immune checkpoint blockade therapies and chimeric antigen receptor …
Pre-metastatic niche: formation, characteristics and therapeutic implication
Y Wang, J Jia, F Wang, Y Fang, Y Yang… - … and Targeted Therapy, 2024 - nature.com
Distant metastasis is a primary cause of mortality and contributes to poor surgical outcomes
in cancer patients. Before the development of organ-specific metastasis, the formation of a …
in cancer patients. Before the development of organ-specific metastasis, the formation of a …
Engineering endogenous tumor‐associated macrophage‐targeted biomimetic nano‐RBC to Reprogram tumor immunosuppressive microenvironment for enhanced …
Y Wang, J Yu, Z Luo, Q Shi, G Liu, F Wu… - Advanced …, 2021 - Wiley Online Library
Immunotherapy has shown encouraging results in various cancers, but the response rates
are relatively low due to the complex tumor immunosuppressive microenvironment (TIME) …
are relatively low due to the complex tumor immunosuppressive microenvironment (TIME) …