Covering: up to 2021 Metagenomics has yielded massive amounts of sequencing data
offering a glimpse into the biosynthetic potential of the uncultivated microbial majority. While …

Lasso peptides are a large and sequence-diverse class of ribosomally synthesized and post-
translationally modified peptide (RiPP) natural products characterized by their slip knot-like …

Cell-free systems are a rapidly expanding platform technology with an important role in the
engineering of biological systems. The key advantages that drive their broad adoption are …

Covering: 2011 up to the end of 2021. Fungal nonribosomal peptides (NRPs) and the
related polyketide–nonribosomal peptide hybrid products (PK–NRPs) are a prolific source of …

Cell-free gene expression (CFE) systems from crude cellular extracts have attracted much
attention for biomanufacturing and synthetic biology. However, activating membrane …

Plastid engineering offers the potential to carry multigene traits in plants; however, it requires
reliable genetic parts to balance expression. The difficulty of chloroplast transformation and …

Advances in genome engineering and associated technologies have reinvigorated natural
products research. Here we highlight the latest developments in the field across the discover …

This review examines a wide range of marine microbial-derived bioactive peptide
molecules, emphasizing the significance of reverse engineering in their production. The …

Engineering regulatory parts for improved performance in genetic programs has played a
pivotal role in the development of the synthetic biology cell programming toolbox. Here, we …

Synthetic Biology is a rapidly growing interdisciplinary field that is primarily built upon
foundational advances in molecular biology combined with engineering design principles …