Despite advances in uncovering the mechanisms that underlie neuroinflammation and
neurodegenerative disease, therapies that prevent neuronal loss remain elusive. Targeting …

Astrocytes play both physiological and pathological roles in maintaining central nervous
system (CNS) function. Here, we review the varied functions of astrocytes and how these …

Astrocytes and microglia are central players in a myriad of processes in the healthy and
diseased brain, ranging from metabolism to immunity. The crosstalk between these two cell …

Here, we reveal an unanticipated role of the blood-brain barrier (BBB) in regulating complex
social behavior in ants. Using scRNA-seq, we find localization in the BBB of a key hormone …

Myelination of axons provides the structural basis for rapid saltatory impulse propagation
along vertebrate fiber tracts, a well-established neurophysiological concept. However …

Polyunsaturated fatty acids (PUFAs) are dietary components participating in
neurotransmission and cell signaling. Pollen is a source of PUFAs for honeybees, and …

Understanding how genotypic variation results in phenotypic variation is especially difficult
for collective behaviour because group phenotypes arise from complex interactions among …

Ecdysone signaling plays central roles in morphogenesis and female ovarian development
in holometabolous insects. In the European honey bee (Apis mellifera L.), however …

Ant colonies with permanent division of labour between castes and highly distinct roles of
the sexes have been conceptualized to be superorganisms, but the cellular and molecular …

In the central nervous system (CNS), functional tasks are often allocated to distinct
compartments. This is also evident in the Drosophila CNS where synapses and dendrites …