Nature's chemical signatures in human olfaction: a foodborne perspective for future biotechnology
A Dunkel, M Steinhaus, M Kotthoff… - Angewandte Chemie …, 2014 - Wiley Online Library
The biocatalytic production of flavor naturals that determine chemosensory percepts of foods
and beverages is an ever challenging target for academic and industrial research. Advances …
and beverages is an ever challenging target for academic and industrial research. Advances …
The olfactory system as marker of neurodegeneration in aging, neurological and neuropsychiatric disorders
N Bhatia-Dey, T Heinbockel - … of environmental research and public health, 2021 - mdpi.com
Research studies that focus on understanding the onset of neurodegenerative pathology
and therapeutic interventions to inhibit its causative factors, have shown a crucial role of …
and therapeutic interventions to inhibit its causative factors, have shown a crucial role of …
The missense of smell: functional variability in the human odorant receptor repertoire
Humans have∼ 400 intact odorant receptors, but each individual has a unique set of
genetic variations that lead to variation in olfactory perception. We used a heterologous …
genetic variations that lead to variation in olfactory perception. We used a heterologous …
Genetic variation across the human olfactory receptor repertoire alters odor perception
C Trimmer, A Keller, NR Murphy… - Proceedings of the …, 2019 - National Acad Sciences
Humans use a family of more than 400 olfactory receptors (ORs) to detect odors, but there is
currently no model that can predict olfactory perception from receptor activity patterns …
currently no model that can predict olfactory perception from receptor activity patterns …
Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci
We report full-length draft de novo genome assemblies for 16 widely used inbred mouse
strains and find extensive strain-specific haplotype variation. We identify and characterize …
strains and find extensive strain-specific haplotype variation. We identify and characterize …
Olfactory perception of chemically diverse molecules
A Keller, LB Vosshall - BMC neuroscience, 2016 - Springer
Background Understanding the relationship between a stimulus and how it is perceived
reveals fundamental principles about the mechanisms of sensory perception. While this …
reveals fundamental principles about the mechanisms of sensory perception. While this …
On 'electronic nose'methodology
P Boeker - Sensors and Actuators B: Chemical, 2014 - Elsevier
Gas measurement systems used with a particular methodology are sometimes referred to as
“Electronic noses”. Traditionally, these systems were based on unspecific gas sensors as …
“Electronic noses”. Traditionally, these systems were based on unspecific gas sensors as …
A Mendelian trait for olfactory sensitivity affects odor experience and food selection
Humans vary in acuity to many odors [1–4], with variation within olfactory receptor (OR)
genes contributing to these differences [5–9]. How such variation also affects odor …
genes contributing to these differences [5–9]. How such variation also affects odor …
Class I odorant receptors, TAS1R and TAS2R taste receptors, are markers for subpopulations of circulating leukocytes
A Malki, J Fiedler, K Fricke, I Ballweg… - Journal of Leucocyte …, 2015 - academic.oup.com
Our cellular immune system has to cope constantly with foodborne substances that enter the
bloodstream postprandially. Here, they may activate leukocytes via specific but yet mostly …
bloodstream postprandially. Here, they may activate leukocytes via specific but yet mostly …
Profiling of olfactory receptor gene expression in whole human olfactory mucosa
C Verbeurgt, F Wilkin, M Tarabichi, F Gregoire… - PloS one, 2014 - journals.plos.org
Olfactory perception is mediated by a large array of olfactory receptor genes. The human
genome contains 851 olfactory receptor gene loci. More than 50% of the loci are annotated …
genome contains 851 olfactory receptor gene loci. More than 50% of the loci are annotated …