C–H activation: toward sustainability and applications

T Dalton, T Faber, F Glorius - ACS Central Science, 2021 - ACS Publications
Since the definition of the “12 Principles of Green Chemistry” more than 20 years ago,
chemists have become increasingly mindful of the need to conserve natural resources and …

Replacement strategies for non-green dipolar aprotic solvents

F Gao, R Bai, F Ferlin, L Vaccaro, M Li, Y Gu - Green Chemistry, 2020 - pubs.rsc.org
Dipolar aprotic solvents (DMSO, DMF, DMAc, NMP, etc.) have been widely used in organic
synthesis and pharmaceutical research because of their remarkable polarities and …

Electropolymerized Bipolar Poly (2, 3‐diaminophenazine) Cathode for High‐Performance Aqueous Al‐Ion Batteries with An Extended Temperature Range of− 20 to …

W Wang, S Zhang, L Zhang, R Wang, Q Ma… - Advanced …, 2024 - Wiley Online Library
Achieving reversible insertion/extraction in most cathodes for aqueous aluminum ion
batteries (AAIBs) is a significant challenge due to the high charge density of Al3+ and strong …

Quantitative sustainability assessment of flow chemistry–from simple metrics to holistic assessment

V Hessel, M Escriba-Gelonch, J Bricout… - ACS Sustainable …, 2021 - ACS Publications
Flow chemistry has changed chemical process designs toward process intensification and is
generally considered as green methodology. In this connection, this perspective provides a …

Sustainable flow approaches to active pharmaceutical ingredients

F Ferlin, D Lanari, L Vaccaro - Green Chemistry, 2020 - pubs.rsc.org
The adoption of flow conditions has been the object of growing attention from both academia
and industry. The shift from batch to continuous-flow technology is very stimulating from a …

Biomass waste-derived Pd–PiNe catalyst for the continuous-flow copper-free sonogashira reaction in a CPME–water azeotropic mixture

F Ferlin, F Valentini, D Sciosci… - ACS Sustainable …, 2021 - ACS Publications
Herein, we report on the development of a waste minimization/valorization methodology
applied to the representative benchmark Sonogashira cross-coupling reaction performed in …

Recent advances and perspectives in manganese-catalyzed C–H activation

T Aneeja, M Neetha, CMA Afsina… - Catalysis Science & …, 2021 - pubs.rsc.org
Manganese-catalyzed C–H activation has emerged as a powerful tool in organic synthesis
within a few years. These reactions are highly selective, eco-friendly and exhibit a wide …

Direct access to functional phenazines via oxidative annulation of anilines and o-phenylenediamines with a reusable cobalt catalyst

Q Liu, C Ci, H Zhao, R **e, HF Jiang, M Zhang - Green Chemistry, 2023 - pubs.rsc.org
Despite the widespread applications of amino phenazines, there is still lacking an efficient
method enabling direct and diverse access to such compounds due to the limited availability …

Electro-oxidative synthesis of phenazines

D Sharma, N Kotwal, P Chauhan - Organic Letters, 2023 - ACS Publications
We disclose herein electro-oxidative synthesis as the general protocol for procuring
phenazines under mild reaction conditions. Using aerial oxygen as an oxidant, inexpensive …

Waste-Minimized Continuous-Flow Synthesis of Oxindoles Exploiting a Polymer-Supported N Heterocyclic Palladium Carbene Complex in a CPME/Water Azeotrope

N Salameh, F Ferlin, F Valentini… - ACS Sustainable …, 2022 - ACS Publications
Herein, we report the development of an effective synthetic protocol for the synthesis of
oxindoles in flow based on a C (sp3)–H activation process promoted by a supported N …