The rapid onset of resistance reduces the efficacy of most conventional antimicrobial drugs
and is a general cause of concern for human well-being. Thus, there is great demand for a …

Members of the genus Bacillus are known to produce a wide arsenal of antimicrobial
substances, including peptide and lipopeptide antibiotics, and bacteriocins. Many of the …

The last decade has seen numerous outbreaks of Clostridium difficile-associated disease
(CDAD), which presented significant challenges for healthcare facilities worldwide. We have …

Bacillus species produce secondary metabolites that are the object of natural product
chemistry studies. The wide structural variability of these compounds has attracted the …

For a long time, the genus Bacillus has been known and considered among the most
applicable genera in several fields. Recent taxonomical developments resulted in the …

The whole organisms can be packaged as biopesticides, but secondary metabolites
secreted by microorganisms can also have a wide range of biological activities that either …

Bacteria produce and excrete a versatile and dynamic suit of compounds to defend against
microbial competitors and mediate local population dynamics. These include a wide range …

The emergence of multidrug-resistant pathogens and the restriction on the use antibiotics as
growth promoters in feed have drawn attention to the search for possible alternatives. Much …

Antimicrobial peptides exhibit high levels of antimicrobial activity against a broad range of
spoilage and pathogenic microorganisms. Compared with bacteriocins produced by lactic …

Bacillus thuringiensis (Bt), a natural pathogen of different invertebrates, primarily insects, is
widely used as a biological control agent. While Bt-based preparations are claimed to be …